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  1. Stiff Person Syndrome Symptoms. Stiff person syndrome most often causes painful muscle contractions and spasms that often begin in the legs and back. Spasms can also affect the abdomen, and less often the upper trunk, arms, neck and face. The spasms can occur in episodes, especially when a person with SPS is surprised or startled, or moves ...

  2. The two main symptoms of stiff person syndrome are: Muscle stiffness or rigidity. Painful muscle spasms. Symptoms can develop at any age, but they most often begin in your 30s and 40s. Stiff person syndrome symptoms can spread to other areas of your body and/or get worse over time.

  3. Oct 13, 2022 · 4 min read. Stiff person syndrome (also known as SPS, Moersch-Woltman syndrome, and stiff man syndrome) is a very rare condition that can cause your muscles to become rigid or spasm....

  4. [2] Signs and symptoms. Stiff-person syndrome (SPS) is often separated into several subtypes, based on the cause and progression of the disease. There are three clinical classifications of SPS: Classic SPS, associated with other autoimmune conditions and usually GAD-positive. Partial SPS variants.

  5. Jul 19, 2024 · Stiff-person syndrome (SPS) is a rare, progressive neurological disorder. Symptoms may include stiff muscles in the trunk (torso), arms, and legs; and greater sensitivity to noise, touch, and emotional distress, which can set off muscle spasms.

  6. The main symptoms of Stiff Person Syndrome are muscle stiffening in the torso and limbs, along with episodes of violent muscle spasms. These can be triggered by environmental stimuli (like loud noises) or emotional stress. The muscle spasms can be so severe that they cause the person to fall down.

  7. Dec 8, 2022 · Stiff-person syndrome is an autoimmune disorder of the nervous system, often resulting in progressive, severe muscle stiffness and spasms of the lower extremities and back. It also can affect other body regions.

  8. Nov 17, 2023 · Symptoms: How Does Stiff Person Syndrome Feel? Stiff person syndrome causes painful stiffness, difficulty walking, problems maintaining balance, and trouble with moving the way you want to. As the condition worsens, it can cause falls, difficulty swallowing, vomiting, or constipation.

  9. www.stiffperson.org › understanding-sps › sps-symptomsSPS Symptoms | The SPSRF

    Understand the symptoms of Stiff Person Syndrome (SPS). Learn about the common signs, including muscle stiffness, spasms, and pain. Explore detailed information to help identify and manage this rare neurological disorder.

  10. Symptoms and Signs |. Diagnosis |. Treatment |. Key Points. Stiff-person syndrome is a CNS disorder that causes progressive muscle stiffness and spasms. (See also Overview of Peripheral Nervous System Disorders.) Stiff-person syndrome (formerly called stiff-man syndrome) affects the central nervous system (CNS) but has neuromuscular manifestations.

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