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  1. Aug 7, 2019 · Introduction. Cardiac arrest is the mode of demise in 30–50% of patients with heart failure and a reduced ejection fraction (HFrEF), and conversely, systolic dysfunction is a major risk factor for sudden cardiac death in the community. 1 Despite their clinical importance, the mechanisms that lead to abrupt circulatory collapse have long been misunderstood.

  2. Dec 19, 2022 · Epilepsy, defined as the tendency for unprovoked seizures, is a common neurologic disease affecting up to 1 in 26 individuals.[1] While the spectrum of comorbidity varies significantly among patients with epilepsy, there is an overall increased mortality risk in this population. Causes of death in individuals with epilepsy include non-epilepsy-related conditions such as suicide, cancers, and ...

  3. Most heart failure (HF) related mortality is due to sudden cardiac death (SCD) and worsening HF, particularly in the case of reduced ejection fraction. Predicting and preventing SCD is an important goal but most works include no or few patients with advanced age, and the prevention of SCD in elderly patients with HF is still controversial.

  4. Jul 18, 2022 · The formal definition of “sudden, unexpected, witnessed or unwitnessed, non-traumatic, and non drowning death in patients with epilepsy” excludes external causes . Research is now targeting the systems that seem most likely to be triggered to malfunction by seizure activity, namely the cardiac, respiratory, and autonomic nervous system [ 4 ].

  5. Oct 25, 2018 · According to a Merck Manual Professional review, the following are some known causes and risk factors for sudden death from respiratory arrest: 1. Acute upper airway obstruction of the throat, epiglottis, vocal chords, pharynx, or trachea with: A mucus plug, food, or vomit. Blood, inflammation, infection.

  6. May 5, 2020 · Introduction. Cardiac arrest is the mode of demise in 30–50% of patients with heart failure and a reduced ejection fraction (HFrEF), and conversely, systolic dysfunction is a major risk factor for sudden cardiac death in the community. 1 Despite their clinical importance, the mechanisms that lead to abrupt circulatory collapse have long been misunderstood.

  7. Summary. Sudden unexpected death in epilepsy (SUDEP) refers to the sudden death of a seemingly healthy individual with epilepsy, usually occurring during, or immediately after, a tonic-clonic seizure. The frequency of SUDEP varies depending on the severity of the epilepsy, but overall the risk of sudden death is more than 20 times higher than ...