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Desloratadine is used to treat allergic rhinitis, nasal congestion and chronic idiopathic urticaria ( hives ). [8] It is the major metabolite of loratadine and the two drugs are similar in safety and effectiveness. [8] Desloratadine is available in many dosage forms and under many brand names worldwide. [9]
Mirtazapine is a tetracyclic piperazinoazepine; mianserin was developed by the same team of organic chemists and mirtazapine differs from it via addition of a nitrogen atom in one of the rings. [114] : 429 [115] [116] It is a racemic mixture of enantiomers. The ( S )- (+)-enantiomer is known as esmirtazapine .
May 17, 2024 · DermNet - Antihistamines (May 17, 2024) antihistamine, any of a group of synthetic drugs that selectively counteract the pharmacological effects of histamine, following its release from certain large cells ( mast cells) within the body. Antihistamines replace histamine at one or the other of the two receptor sites at which it becomes bound in ...
Jan 31, 2022 · Sedative effect of antihistamines of the first generation is the result of their lipophilicity and the ability to penetrate the blood-brain barrier and bind to the H1-histamine receptors of the brain. In addition, sedation can be caused by blocking the central serotonin and acetylcholine receptors. The severity of the sedative effect of ...
Infobox references. Phenothiazine, abbreviated PTZ, is an organic compound that has the formula S (C 6 H 4) 2 NH and is related to the thiazine -class of heterocyclic compounds. Derivatives of phenothiazine are highly bioactive and have widespread use and rich history.
Histamine agonist. A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes. H 2: Betazole and Impromidine are examples of agonists used in diagnostics to increase histamine. H 3: Betahistine is a weak Histamine 1 agonist and a very strong antagonist of the Histamine 3 autoreceptor.
Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is produced by Allergan and marketed by Inspire in the United States. [1] It is highly selective for the H 1 receptor and does not cross the blood-brain-barrier.
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