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Mar 27, 2002 · Milstein was born in 1927 in Bahia Blanca, Argentina, the middle of three sons. His father was a salesman, his mother a schoolteacher. His family were active in the local Jewish community but non-religious. Though he rarely entered a synagogue, César Milstein was proud of his Argentinian Jewish origins. As a child he was bright, but neither ...
Department of Biochemistry PhD student (1958-1961, PhD awarded 1961). César Milstein was born in Bahía Blanca, Argentina and studied at the University of Buenos Aires, completing a PhD on the enzyme aldehyde dehydrogenase. This led him to Cambridge to work on phosphoglucomutase with Malcolm Dixon in the Department of Biochemistry.
Backbone model of an antibody. César Milstein and Georges Köhler were trying to understand the mechanisms responsible for the remarkable diversity of antibodies. Through this research, they invented a way to stimulate cells to provide unlimited production of a specific antibody – a monoclonal antibody.
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Apr 30, 2002 · César Milstein, who died on 24 March, spent the major part of his research career working on antibodies, making outstanding contributions to both areas. Behring's discovery was recognised by the award in 1901 of the first Nobel Prize in Physiology or Medicine. Milstein and Köhler's discovery of monoclonal antibodies was recognised in the 1984 ...
Feb 1, 2004 · I am in a good position to comment on the early history of monoclonal antibodies because when César Milstein was a beginner at in vitro cell culture, his tissue-culture laboratory was next to ...
Mar 24, 2002 · César Milstein died in the early hours of 24th March 2002. He had a long history of cardiovascular illness, to which he finally succumbed. We will always remember his enthusiasm for science and his kind attention to the problems of others. His most famous contribution to biology was the invention of monoclonal antibodies (also called hybridomas, but that was a term he never really liked) for ...
