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  1. Oct 10, 2007 · The signs and symptoms of sepsis are influenced by the virulence of the pathogen, the portal of entry, the susceptibility and response of the host, and the temporal evolution of the condition Sepsis is a clinical diagnosis; microbiological investigations are commonly negative

  2. Nov 23, 2021 · The International Pediatric Sepsis Conference in 2005 published a definition and criteria for diagnosing sepsis, severe sepsis and septic shock in children. 3 This was based on the then existing understanding and definitions for adult sepsis with modifications based on age and differences in physiology in children (see Table 1 for definitions).

  3. Jun 30, 2016 · Sepsis is the dysregulated systemic inflammatory and immune response to infection that produces organ injury. Septic shock is characterized by persistent hypotension that substantially increases ...

  4. Mar 21, 2019 · Sepsis is a medical emergency that describes the body’s systemic immunological response to an infectious process that can lead to end-stage organ dysfunction and death. Despite significant advancements in the understanding of the pathophysiology of this clinical syndrome, advancements in hemodynamic monitoring tools, and resuscitation measures, sepsis remains one of the major causes of ...

  5. Feb 10, 2023 · Overview Sepsis is a serious condition in which the body responds improperly to an infection. The infection-fighting processes turn on the body, causing the organs to work poorly. Sepsis may progress to septic shock. This is a dramatic drop in blood pressure that can damage the lungs, kidneys, liver and other organs. When the damage is severe, it can lead to death. Early treatment of sepsis ...

  6. NHS information about the symptoms of sepsis in children and adults, and where and when to get help.

  7. May 5, 2020 · Who it Hurts: While sepsis is an equal-opportunity killer, impacting the sick, the well, and people of all ages, some groups are more likely to be affected. These include very young children, older adults, and those with a weakened immune system.