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Mar 10, 2022 · Use alpha blockers with caution: In cataract surgery as there is a risk for intra-operative floppy iris syndrome. In hypotension Also, avoid the use of alpha blockers with other drugs that lower blood pressure or PDE-5 inhibitors due to additive hypotensive effects.
Alpha blockers are the most effective, least costly, and best tolerated of the drugs for relieving LUTS. Four long-acting alpha 1 blockers are approved by the Food and Drug Administration for treatment of symptomatic LUTS/BPH: terazosin, doxazosin, tamsulosin, and alfuzosin. All are well tolerated and have comparable dose-dependent effectiveness.
Alpha blockers affect the sympathetic nervous system and work by inhibiting alpha receptors. Alpha receptors are of two types: alpha receptor 1 and alpha receptor 2. Alpha 1 receptors are present on the vascular smooth muscle of the skin, sphincters of the gastrointestinal system, kidney, and brain. They cause constriction of the vessels when ...
Aug 22, 2023 · a light-headed feeling, like you might pass out; or. a painful erection that lasts 4 hours or longer. Common tamsulosin side effects may include: abnormal ejaculation, decreased amount of semen; dizziness, drowsiness, weakness; runny or stuffy nose, sore throat, cough; back pain, chest pain, headache; nausea, diarrhea;
May 25, 2007 · Alpha 1 ‐adrenergic antagonists are most effective in low and medium plasma renin activity states. 28 Studies have been inconsistent as to the effect of age and race on the BP‐lowering response to these drugs. 18 , 19 , 29 Alpha 1 ‐adrenergic antagonists may find their greatest use as add‐on therapy to other antihypertensives.
Dec 25, 2017 · Guidelines also support alpha-blockers for MET. Additionally, long-term alpha-blocker use may be a viable method to prevent stone recurrence. Tamsulosin 0.4 mg daily is the alpha-blocker and dose with the most data to support its use in stone treatment.
Alpha-blockers are usually used if other drugs are not working well or are not suitable for you. For example, if you have side effects, have other health problems or are taking certain medications. They’re not usually one of the first one’s you’ll try because other medicines seem to be better at protecting you from a heart attack or ...
