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Mercenary Frank Martin (Jason Statham) has accepted a job that seems easy enough, as chauffeur and bodyguard to young Jack (Hunter Clary), son of crusading politician Jefferson Billings (Matthew Modine). The problem is that Billings is crusading against an international drug cartel. They retaliate by kidnapping Jack and infecting him with a deadly and highly contagious virus. Responsible for the boy, Frank must reclaim him and then find an antidote before scores of innocents are stricken.