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  1. Masters of Sex: Created by Michelle Ashford. With Michael Sheen, Lizzy Caplan, Caitlin FitzGerald, Annaleigh Ashford. Drama about the pioneers of the science of human sexuality whose research touched off the sexual revolution.

    • (39K)
    • 2013-09-29
    • Drama, Romance
    • 60
  2. Masters of Sex is an American period drama television series that premiered on September 29, 2013, on Showtime. [1] It was developed by Michelle Ashford and loosely based on Thomas Maier's biography Masters of Sex. [2]

    • Period Drama
  3. Find out how to watch Masters of Sex. Stream the latest seasons and episodes, watch trailers, and more for Masters of Sex at TV Guide.

    • (69)
    • 5
    • TVMA
  4. Synopsis. William Masters and Virginia Johnson are real-life pioneers of the science of human sexuality. Their research touched off the sexual revolution and took them from a midwestern teaching hospital to the cover of Time magazine and multiple appearances on Johnny Carson's couch.

    • 4
    • TV-MA
    • 8
  5. Masters of Sex tells the story of Dr. William Masters (Michael Sheen) and Virginia Johnson (Lizzy Caplan), two pioneering researchers of human sexuality at Washington University in St. Louis. The first season takes place between 1956 and 1958.

  6. Dr. William Masters runs a successful medical practice and conducts a secret study of human sexuality; a former nightclub singer proves to be an asset to Masters' work. Johnson considers her...

  7. Sep 29, 2013 · As Masters (Michael Sheen) and Libby (Caitlin Fitzgerald) struggle with the fallout from her miscarriage, Johnson (Lizzy Caplan) proposes a study that challenges Freud’s theories of female sexual response.

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