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  1. Brothers & Sisters is an American family drama television series that centers on the Walker family and their lives in Los Angeles and Pasadena, California. The series aired for five seasons on ABC from September 24, 2006, to May 8, 2011. For the entirety of its run, it was broadcast on Sunday nights following Desperate Housewives.

  2. Brothers & Sisters: Created by Jon Robin Baitz. With Dave Annable, Calista Flockhart, Rachel Griffiths, Ron Rifkin. The story of the drama surrounding a family's adult siblings.

    • (25K)
    • 2006-09-24
    • Drama
    • 60
  3. Watch the official Brothers and Sisters online at ABC.com. Get exclusive videos, blogs, photos, cast bios, free episodes.

  4. Browse the episodes of Brothers & Sisters, a drama series about a family coping with loss, love and secrets. See the titles, dates, ratings and summaries of each episode.

    • Brothers and Sisters1
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    • Brothers and Sisters5
  5. Watch five seasons of Brothers & Sisters, a show about the Walkers, a dysfunctional but loving family. Stream episodes, extras, and details on Hulu with plans starting at $7.99/month.

    • Dave Annable
    • September 24, 2006
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  7. episodes. Brothers & Sisters is a family drama that premiered on ABC on September 24, 2006, and concluded on May 8, 2011. A total of 109 episodes of Brothers & Sisters have aired over five seasons.

  8. A drama series about the Walker family, who cope with various challenges after the death of their patriarch. Watch seasons 1-5 on Hulu, Fandango, Prime Video or Apple TV.

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