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- Season 2 overviewSep 12, 1990-May 1, 199125 episodesSeason 2 episodes1. Doogenstein Sep 12, 1990
- Increasing responsibility makes Doogie lament the loss of youth.
- 2. Guess Who's Coming to Doogie's Sep 19, 1990
- The man who held Doogie and Vinnie hostage visits the hospital.
- 3. Ask Dr. Doogie Sep 26, 1990
- A series of TV public service announcements makes Doogie a star.
- 4. C'est la Vinnie Oct 3, 1990
- Vinnie is stuck in an elevator with his pregnant teacher (Mimi Kuzyk).
- 5. Car Wars Oct 10, 1990
- Doogie gets a classic car, but his father forbids him to keep it.
- 6. Doogie Sings the Blues Oct 17, 1990
- A homeless patient (Joe Seneca) claims to be a legendary jazz musician.
- 7. Academia Nuts Oct 24, 1990
- Vinnie passes off an old biology paper that Doogie wrote as his own.
- 8. Revenge of the Teenage Dead Oct 31, 1990
- Vinnie directs a video, and decides to cast a nerd in the slasher role.
- 9. Nautilus for Naught Nov 7, 1990
- Wanda admires the physique of a male model, inspiring Doogie to hit the gym.
- 10. Don't Let the Turkeys Get You Down Nov 14, 1990
- Katherine's parents come to visit for Thanksgiving; Vinnie and Janine's relationship hits a snag.
- 11. Oh Very Young Nov 28, 1990
- Canfield dates Spaulding; Doogie applies for elite surgical training.
- 12. TV or Not TV Dec 5, 1990
- Vinnie and the staff hound a hospitalized network president to help Vinnie get into film school.
- 13. A Woman Too Far Dec 12, 1990
- Doogie cheats on Wanda, then must defend a bigamist to his wives.
- 14. Presumed Guilty Jan 2, 1991
- Vinnie damages Mr. Howser's prized '57 convertible; Doogie and Katherine try to help.
- 15. To Live and Die in Brentwood Jan 9, 1991
- Doogie struggles to help when an unexpected death strikes Wanda's family.
- 16. Air Doogie Jan 23, 1991
- Inept basketball player Doogie gets imagined advice from Julius Erving.
- 17. A Life in Progress Jan 30, 1991
- A muralist working in the hospital has AIDS and is fired from his job.
- 18. My Two Dads Feb 6, 1991
- Doogie and his father bring Vinnie along on their father/son camping trip.
- 19. Nobody Expects the Spanish Inquisition Feb 13, 1991
- Doogie and his grandfather run into problems when they help remodel the kitchen.
- 20. Fatal Distraction Feb 20, 1991
- Doogie finds himself attracted to a nursing student during a break with Wanda.
- 21. The Doctor, the Wife, Her Son and Her Job Mar 13, 1991
- Doogie is embarrassed and annoyed by Katherine's job at the hospital.
- 22. Planet of the Dateless Mar 20, 1991
- McGuires envies Doogie's talent; Doogie accepts a blind date and demonstrates his maturity.
- 23. Doogie's Wager Apr 3, 1991
- Delivering a premature baby poses a challenge for Doogie; Vinnie awaits his film school acceptance.
- 24. A Kiss Ain't Just a Kiss Apr 24, 1991
- Janine finds out that Vinnie is cheating on her, and seeks comfort from Doogie.
- 25. Dances With Wanda May 1, 1991
- Doogie wants to take a grieving and reclusive Wanda to the senior prom.