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    How does cholera kill you?

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  2. Cholera - HISTORY

    www.history.com/topics/inventions/history-of-cholera

    Mar 24, 2020 · And of the people who do develop cholera, 20 percent come down with severe symptoms, which includes severe diarrhea, vomiting, and leg cramps. These symptoms can cause dehydration, septic shock and...

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  3. Pandemics That Changed History: Timeline - HISTORY

    www.history.com/topics/middle-ages/pandemics...

    Apr 01, 2020 · Symptoms included fever, sore throat, diarrhea and, if the patient lived long enough, pus-filled sores. This plague continued until about 180 A.D., ... 1817: First Cholera Pandemic.

  4. How 5 of History’s Worst Pandemics Finally Ended

    www.history.com/news/pandemics-end-plague...
    • Plague of Justinian—No One Left to Die
    • Black Death—The Invention of Quarantine
    • The Great Plague of London—Sealing Up The Sick
    • Smallpox—A European Disease Ravages The New World
    • Cholera—A Victory For Public Health Research

    Three of the deadliest pandemics in recorded history were caused by a single bacterium, Yersinia pestis, a fatal infection otherwise known as the plague. The Plague of Justinian arrived in Constantinople, the capital of the Byzantine Empire, in 541 CE. It was carried over the Mediterranean Sea from Egypt, a recently conquered land paying tribute to Emperor Justinian in grain. Plague-ridden fleas hitched a ride on the black rats that snacked on the grain. The plague decimated Constantinople and spread like wildfire across Europe, Asia, North Africa and Arabia killing an estimated 30 to 50 million people, perhaps half of the world’s population. “People had no real understanding of how to fight it other than trying to avoid sick people,” says Thomas Mockaitis, a history professor at DePaul University. “As to how the plague ended, the best guess is that the majority of people in a pandemic somehow survive, and those who survive have immunity.”

    The plague never really went away, and when it returned 800 years later, it killed with reckless abandon. The Black Death, which hit Europe in 1347, claimed an astonishing 200 million lives in just four years. As for how to stop the disease, people still had no scientific understanding of contagion, says Mockaitis, but they knew that it had something to do with proximity. That’s why forward-thinking officials in Venetian-controlled port city of Ragusa decided to keep newly arrived sailors in isolation until they could prove they weren’t sick. At first, sailors were held on their ships for 30 days, which became known in Venetian law as a trentino. As time went on, the Venetians increased the forced isolation to 40 days or a quarantino, the origin of the word quarantine and the start of its practice in the Western world. “That definitely had an effect,” says Mockaitis. READ MORE: How Rats and Fleas Spread the Black Death

    London never really caught a break after the Black Death. The plague resurfaced roughly every 20 years from 1348 to 1665—40 outbreaks in 300 years. And with each new plague epidemic, 20 percent of the men, women and children living in the British capital were killed. By the early 1500s, England imposed the first laws to separate and isolate the sick. Homes stricken by plague were marked with a bale of hay strung to a pole outside. If you had infected family members, you had to carry a white pole when you went out in public. Cats and dogs were believed to carry the disease, so there was a wholesale massacre of hundreds of thousands of animals. The Great Plague of 1665 was the last and one of the worst of the centuries-long outbreaks, killing 100,000 Londoners in just seven months. All public entertainment was banned and victims were forcibly shut into their homes to prevent the spread of the disease. Red crosses were painted on their doors along with a plea for forgiveness: “Lord hav...

    Smallpox was endemic to Europe, Asia and Arabia for centuries, a persistent menace that killed three out of ten people it infected and left the rest with pockmarked scars. But the death rate in the Old World paled in comparison to the devastation wrought on native populations in the New World when the smallpox virus arrived in the 15th century with the first European explorers. The indigenous peoples of modern-day Mexico and the United States had zero natural immunity to smallpox and the virus cut them down by the tens of millions. “There hasn’t been a kill off in human history to match what happened in the Americas—90 to 95 percent of the indigenous population wiped out over a century,” says Mockaitis. “Mexico goes from 11 million people pre-conquest to one million.” Centuries later, smallpox became the first virus epidemic to be ended by a vaccine. In the late 18th-century, a British doctor named Edward Jenner discovered that milkmaids infected with a milder virus called cowpox se...

    In the early- to mid-19th century, choleratore through England, killing tens of thousands. The prevailing scientific theory of the day said that the disease was spread by foul air known as a “miasma.” But a British doctor named John Snow suspected that the mysterious disease, which killed its victims within days of the first symptoms, lurked in London’s drinking water. Snow acted like a scientific Sherlock Holmes, investigating hospital records and morgue reports to track the precise locations of deadly outbreaks. He created a geographic chart of cholera deaths over a 10-day period and found a cluster of 500 fatal infections surrounding the Broad Street pump, a popular city well for drinking water. “As soon as I became acquainted with the situation and extent of this irruption (sic) of cholera, I suspected some contamination of the water of the much-frequented street-pump in Broad Street,” wrote Snow. With dogged effort, Snow convinced local officials to remove the pump handle on th...

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  5. Pandemics - HISTORY

    www.history.com/tag/pandemics

    Cholera tore through New York City in the summer of 1832, leaving its victims with sunken eyes, blue skin, severe diarrhea, nausea and vomiting.

  6. The Russian Flu of 1889: The Deadly Pandemic Few Americans ...

    www.history.com/news/1889-russian-flu-pandemic...

    Mar 23, 2020 · Their household’s outbreak had begun with sudden chills and headaches, reports said, followed by sore throat, laryngitis and bronchitis. Overall, “the patients were about as sick as persons with a...

    • Greg Daugherty
  7. PTSD and Shell Shock - HISTORY

    www.history.com/topics/inventions/history-of...

    Aug 21, 2018 · They may also experience increased arousal and reactive symptoms, such as feeling jumpy (startling easy), having problems concentrating or sleeping, being easily angered or irritated and engaging...

  8. Spanish Flu - Symptoms, How It Began & Ended - HISTORY

    www.history.com/topics/world-war-i/1918-flu-pandemic

    May 19, 2020 · The first wave of the 1918 pandemic occurred in the spring and was generally mild. The sick, who experienced such typical flu symptoms as chills, fever and fatigue, usually recovered after several...

  9. Influenza - Causes, Treatments & Pandemics - HISTORY

    www.history.com/topics/inventions/flu

    Feb 05, 2020 · Influenza is a viral respiratory infection that causes symptoms similar to, but more severe than, the common cold. Flu symptoms can include sudden onset fever, cough, runny or stuffy nose and ...

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