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Cytochromes P450 ( P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases.
- Xenobiotic
A xenobiotic is a chemical substance found within an...
- Cordyline Rubra
Main page; Contents; Current events; Random article; About...
- Cytochrome P450 Reductase
Cytochrome P450 reductase (also known as...
- CYP3A4
Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is...
- Xenobiotic
Apr 24, 2023 · Fundamentals. Cytochrome p450 is a superfamily of membrane-bound hemoprotein isozymes with distinct classifications. While present in most body tissues, CYP enzymes predominantly occupy the liver, intestines, and kidneys, with their highest concentration in the liver.
- Brian Gilani, Manouchkathe Cassagnol
- 2020
Oct 1, 2009 · Abstract. The Cytochrome P450 Homepage is a universal resource for nomenclature and sequence information on cytochrome P450 ( CYP) genes. The site has been in continuous operation since February 1995. Currently, naming information for 11,512 CYPs are available on the web pages.
- David R Nelson
- 10.1186/1479-7364-4-1-59
- 2009
- Hum Genomics. 2009; 4(1): 59-65.
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Abstract. Background: The cytochrome P450 (CYP) enzymes are membrane-bound hemoproteins that play a pivotal role in the detoxification of xenobiotics, cellular metabolism and homeostasis. Induction or inhibition of CYP enzymes is a major mechanism that underlies drug-drug interactions.
Dec 8, 2000 · Cytochrome P450 proteins, named for the absorption band at 450 nm of their carbon-monoxide-bound form, are one of the largest superfamilies of enzyme proteins. The P450 genes (also called CYP) are found in the genomes of virtually all organisms, but their number has exploded in plants.
