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  1. Oct 30, 2023 · The substantia nigra, also known as the black nucleus, is a large gray matter structure of the mesencephalon or midbrain (middle brain). It gets its name from its dark appearance on the cross-sections of the brain ( Latin for 'Black substance'). The dark coloration comes from the high number of neurons that contain the substance neuromelanin .

  2. The substantia nigra (SN) is a midbrain dopaminergic nucleus which has a critical role in modulating motor movement and reward functions as part of the basal ganglia circuitry. It is one of the brainstem nuclei and part of the extrapyramidal system.

  3. Dec 8, 2023 · The Substantia Nigra, Latin forblack substance,” is aptly named for its dark coloration, a result of high levels of neuromelanin in dopaminergic neurons. This structure is situated in the midbrain, an area that connects the forebrain and hindbrain, playing a pivotal role in motor control and a host of other functions.

  4. Nov 3, 2023 · Substantia nigra. Tectum. Blood supply. Functions overview. Clinical relations. Infarction of the midbrain. Parinaud’s syndrome. Weber’s syndrome. Argyll Roberston pupil (“prostitute’s pupils”) Sources. + Show all. Gross anatomy. The midbrain lies between the thalamus (rostrally) and pons (caudally).

  5. Quick Facts. The substantia nigra is located in the midbrain and plays an important role in reward, addiction and movement. The substantia nigra appears darker than neighboring areas, due to high levels of melanin in dopaminergic neurons. Parkinson's disease is characterized by the death of dopaminergic neurons in the substantia nigra.

  6. The substantia nigra is a region in the midbrain that is considered part of the basal ganglia. It looks like a darkened streak in unstained brain tissue; this is where it gets its name, which is Latin for "black substance." Although it is often referred to as one structure, there are actually two substantia nigrae, one on each side of the ...

  7. Aug 17, 2019 · Answer: The substantia nigra is a midbrain structure that is part of the basal ganglia and is important for movement. The substantia nigra is a brain structure located in the midbrain. It is part of a series of interconnected structures called the basal ganglia.

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