Search results
How is morbilliform drug eruption diagnosed? A strong clinical suspicion of morbilliform drug eruption depends on: Typical exanthematous rash; Recently introduced medication; To identify the possible causative drug, a drug calendar, including all prescribed and over-the counter products, may be helpful. The starting date of each new drug is ...
Acute or subacute adverse cutaneous reactions to a drug or medicine include drug eruptions. There are many types of drug eruption, which range from a clinically mild and unnoticed rash to a severe cutaneous adverse reaction (SCAR) that may be life-threatening.
People also ask
What is a morbilliform rash?
How long does a morbilliform rash last?
Can antibiotics cause a morbilliform rash?
Morbilliform drug eruption; Drug hypersensitivity syndrome. Acute connective tissue diseases can present with an exanthem: Systemic lupus erythematosus; Systemic-onset juvenile arthritis; Adult-onset Still disease. Some exanthems are of unknown cause, for example, Kawasaki disease. What are the signs and symptoms of exanthems?
Many antibiotics cause morbilliform eruptions. A morbilliform rash usually starts within 7–14 days of starting a new antibiotic, and lasts for 5–10 days. It may occur more quickly on re-exposure to the same drug. It can look similar to a viral exanthem but is usually pruritic, whereas similar viral rashes are not particularly itchy.
Acute measles is usually confirmed on a viral nasopharyngeal or throat swab analysed by polymerase chain reaction (PCR). Blood and urine samples can also be used. This should be done within 5 days of onset of rash, however, positive results are sometimes obtained up to 10–14 days after the rash has resolved.
Fever and rash are the commonest signs. The rash begins as a patchy or diffuse redness (morbilliform) and progresses to small and large tense blisters because of skin swelling (oedema). Swelling of the face is a particular feature. The rash then spreads to involve the body, arms and legs. Mucous membranes are not affected.
DIHS/DRESS typically presents with erythematous papules and plaques, or a morbilliform eruption. The most common haematological finding is eosinophilia. DIHS/DRESS has a latency period of 2–6 weeks between drug exposure and the onset of illness.
