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    • Her daughter suffers from Henoch-Schönlein purpura

      • She'd just wrapped a project in Belfast and "my beloved little girl who was 3 at the time became suddenly very ill," Waddingham says of learning her daughter suffers from Henoch-Schönlein purpura or HSP, a painful auto-immune disorder that causes inflammation and bleeding in the small blood vessels, resulting in rashes and sore joints.
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  2. Mar 30, 2023 · She'd just wrapped a project in Belfast and "my beloved little girl who was 3 at the time became suddenly very ill," Waddingham says of learning her daughter suffers from...

  3. Feb 27, 2024 · The Ted Lasso actress told PEOPLE in March 2023 that she found out her daughter was diagnosed with Henoch-Schönlein purpura or HSP, a painful autoimmune disorder that causes inflammation...

    • Rebecca Aizin
  4. Mar 31, 2023 · Recalling the period, Waddingham says her daughter Kitty was diagnosed with the rare immune-mediated condition Henoch-Schönlein purpura (HSP). HSP, according to the NHS is a disorder that...

  5. Sep 21, 2021 · Henoch-Schönlein purpura (HSP) involves swelling of small blood vessels. Waddingham, 47, vowed to be closer to her child after the scare. After 'asking the universe' for help, she...

    • George Stark
    • 1 min
    • Fast Facts
    • First Description
    • Who Gets Henoch-Schönlein Purpura (The “Typical” Patient)?
    • What Causes Henoch-Schönlein Purpura?
    • How Is Henoch-Schönlein Purpura Diagnosed?
    • Treatment and Course of Henoch-Schönlein Purpura
    • Living with HSP
    HSP is usually self-limited. Therefore, treatment is not indicated in all cases, and full recovery is the rule.
    HSP is more common in children than adults, but has a tendency to be more severe when it occurs in adults.
    In a small minority of cases, HSP can cause severe kidney or bowel disease.

    Dr. William Heberden, a London physician, described the first cases of Henoch-Schönlein purpura (HSP) in 1801. In describing HSP, Heberden wrote of a 5-year old boy who “…was seized with pains and swellings in various parts…He sometimes had pains in his belly with vomiting…and the urine was tinged with blood. Presently, the skin of his leg was all ...

    Usually, HSP affects a child shortly after an upper respiratory infection has resolved. HSP is the most common form of vasculitis in children, with an annual incidence on the order of 140 cases/million persons. The mean age of patients with HSP is 5.9 years.

    In two-thirds of the cases, the disease follows an upper respiratory tract infection, with onset an average of ten days after the start of respiratory symptoms. Despite this association, no single microorganism or environmental exposure has been confirmed as an important cause of HSP.

    Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of HSP. The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often observed. However, all four elements of this tetrad are not required for diagnosis. The microscopic hallmark of HSP is the deposition of IgA (an anti...

    NSAIDs may alleviate arthralgias but can aggravate gastrointestinal symptoms, and should be avoided in any patient with renal disease. Dapsone (100 mg/day) may be effective in cases of HSP, perhaps through disrupting the abnormal immune response. Although steroids have not been evaluated rigorously in HSP, they appear to ease joint and gastrointest...

    Supportive care may involve a short course of prednisone or an NSAID, such as naprosyn or ibuprofen, if the kidneys are not involved. Keeping the legs elevated may help prevent purpura during flares of active disease. Additionally, many patients’ purpura will recur after they start to feel better and become more active, inherently increasing their ...

  6. Aug 15, 2020 · Henoch-Schönlein purpura, now called immunoglobulin A (IgA) vasculitis, is a systemic, immune complex–mediated, small-vessel leukocytoclastic vasculitis characterized by nonthrombocytopenic ...

  7. Sep 21, 2021 · Many children with Henoch-Schonlein purpura develop belly pain, nausea, vomiting and bloody stools. These symptoms sometimes occur before the rash appears. Kidney involvement.

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