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  1. Jan 1, 2014 · Neonatal sepsis continues to be a common and significant health care burden, especially in very-low-birth-weight infants (VLBW<1500 g). Though intrapartum antibiotic prophylaxis has decreased the incidence of early-onset group B streptococcal infection dramatically, it still remains a major cause …

    • Birju A Shah, James F Padbury
    • 2014
  2. Neonatal sepsis continues to be a common and significant health care burden, especially in very-low-birth-weight infants (VLBw <1500 g). Though intrapartum antibiotic prophylaxis has decreased the incidence of early-onset group B strepto-coccal infection dramatically, it still remains a major cause of neonatal sepsis.

  3. Knowing how quickly neonates with sepsis can deteriorate, clinicians tend to be cautious and have a low threshold for giving antibiotics. Even with full access to laboratory support the diagnosis is not easy; biomarkers such as C reactive protein and procalcitonin are unreliable.

    • Elizabeth Molyneux, Al Gest
    • 2015
  4. Nov 1, 2013 · Neonatal sepsis continues to be a common and significant health care burden, especially in very-low-birth-weight infants (VLBW <1500 g). Though intrapartum antibiotic prophylaxis has decreased the incidence of early-onset group B streptococcal infection dramatically, it still remains a major cause of neonatal sepsis.

  5. Feb 9, 2023 · Nevertheless, sepsis remains a major medical problem in neonates . Depending on the time of clinical presentation and the origin of the causative pathogens, it is defined as early-onset sepsis (EOS) when occurring ≤72 h after birth (or by others during the first 7 post-natal days), and as late-onset sepsis (LOS) when it presents thereafter ...

  6. Sep 19, 2023 · We discuss the maternal and neonatal risk factors involved in the pathogenesis of neonatal sepsis and the signs and symptoms of early and late neonatal sepsis. We focus on the different pathogens involved and the markers used in the diagnosis and treatments available for each.

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  8. Nov 2, 2021 · Neonatal sepsis is a clinical syndrome characterized by nonspecific signs and symptoms caused by invasion by pathogens. 1, 2 Sepsis is deemed culture-proven if confirmed by microbial growth on...

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