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  1. Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [1] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF) is increasingly being recognized. [2]

  2. Carbon tetrachloride is another toxin that can cause acute liver failure. It is an industrial chemical found in refrigerants and solvents for waxes, varnishes and other materials. Autoimmune disease. Liver failure can be caused by autoimmune hepatitis — a disease in which your immune system attacks liver cells, causing inflammation and injury.

  3. Apr 1, 2024 · Acute-on-chronic liver failure (ACLF) is when a person with chronic liver disease experiences an acute event—such as alcohol-related injury, drug-induced injury, or a liver infection—that causes the abrupt loss of liver function. Although ACLF is often reversible, it is usually a sign of severe disease progression.

  4. Feb 13, 2024 · Liver problems Enlarge image. Liver disease doesn't always cause symptoms that can be seen or felt. If there are symptoms of liver disease, they may include: Yellowing of the skin and the whites of the eyes, called jaundice. Yellowing of the skin might be harder to see on Black or brown skin. Belly pain and swelling.

  5. Vomiting blood. Blood in the stool. As liver failure advances, symptoms become more severe. In later stages, symptoms of liver failure may include: Jaundice (yellowing of your skin and eyes). Extreme tiredness. Disorientation (confusion and uncertainty). Fluid buildup in your abdomen and extremities (arms and legs).

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