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  1. Few independent risk factors for late-onset sepsis have been identified, the most common being birth gestational age and parenteral nutrition. Further work is required to validate that these...

  2. Nov 1, 2022 · This article provides an overview of the epidemiology, risk factors, diagnostic tools, and treatment options of LOS in the context of increasing numbers of extremely preterm infants. It addresses the question of whether LOS could be identified earlier and more precisely to allow for earlier and more targeted therapy and discusses rational ...

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  4. Nov 11, 2022 · Due to a lack of sensitivity and specificity, sepsis definitions based upon systemic inflammatory response syndrome (SIRS) criteria have largely been abandoned in adult patients, with a shift to metrics focused on infection-associated organ dysfunction that also have utility in predicting sepsis-attributable morbidity and mortality. 50 51 ...

  5. Jul 15, 2008 · Abstract. Neonates are one of the highest risk groups of hospitalized patients for sepsis. There is a wide variation in the incidence and microbial causes of late-onset neonatal sepsis, owing to differences in both patient populations and standards of care in the individual neonatal units.

    • James W Gray
    • 2008
  6. Jul 15, 2008 · Few independent risk factors for late-onset sepsis have been identified, the most common being birth gestational age and parenteral nutrition, and these observations could be used to stratify infection rates in multicenter surveillance schemes. Neonates are one of the highest risk groups of hospitalized patients for sepsis.

  7. Jul 24, 2018 · Results. We identified 444 episodes of blood culture-proven sepsis in 429 infants; 20% of cases were EOS, 62% hospital-acquired LOS, and 18% community-acquired LOS. The estimated national incidence of EOS, hospital-acquired LOS, and community-acquired LOS was 0.28 (95% CI 0.23-0.35), 0.86 (0.76-0.97), and 0.28 (0.23-0.34) per 1000 livebirths.

  8. Aug 1, 2008 · Gram-negative bloodstream infections (BSIs) cause 20-30% of late onset sepsis in neonatal intensive care unit (NICU) patients and have mortality rates of 30-50%.

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