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Key points. Dengue viruses are usually spread to people through the bites of infected Aedes species mosquitoes. A person infected with dengue during pregnancy can pass the virus to their fetus. Rarely, dengue can be spread through other routes. Through mosquito bites.
- Key Facts
- Overview
- Symptoms
- Diagnostics and Treatment
- Global Burden
- Transmission
- Risk Factors
- Prevention and Control
- Who Response
Dengue is a viral infection transmitted to humans through the bite of infected mosquitoes.About half of the world's population is now at risk of dengue with an estimated 100–400 million infections occurring each year.Dengue is found in tropical and sub-tropical climates worldwide, mostly in urban and semi-urban areas.While many dengue infections are asymptomatic or produce only mild illness, the virus can occasionally cause more severe cases, and even death.Dengue (break-bone fever) is a viral infection that spreads from mosquitoes to people. It is more common in tropical and subtropical climates. Most people who get dengue will not have symptoms. But for those who do, the most common symptoms are high fever, headache, body aches, nausea, and rash. Most will get better in 1–2 weeks. Some people develo...
Most people with dengue have mild or no symptoms and will get better in 1–2 weeks. Rarely, dengue can be severe and lead to death. If symptoms occur, they usually begin 4–10 days after infection and last for 2–7 days. Symptoms may include: 1. high fever (40°C/104°F) 2. severe headache 3. pain behind the eyes 4. muscle and joint pains 5. nausea 6. v...
There is no specific treatment for dengue. The focus is on treating pain symptoms. Most cases of dengue fever can be treated at home with pain medicine. Acetaminophen (paracetamol) is often used to control pain. Non-steroidal anti-inflammatory drugs like ibuprofen and aspirin are avoided as they can increase the risk of bleeding. For people with se...
The incidence of dengue has grown dramatically around the world in recent decades, with cases reported to WHO increasing from 505 430 cases in 2000 to 5.2 million in 2019. A vast majority of cases are asymptomatic or mild and self-managed, and hence the actual numbers of dengue cases are under-reported. Many cases are also misdiagnosed as other feb...
Transmission through the mosquito bite The dengue virus is transmitted to humans through the bites of infected female mosquitoes, primarily the Aedes aegypti mosquito. Other species within the Aedes genus can also act as vectors, but their contribution is normally secondary to Aedes aegypti. However, in 2023, a surge in local transmission of dengue...
Previous infection with DENV increases the risk of the individual developing severe dengue. Urbanization (especially unplanned), is associated with dengue transmission through multiple social and environmental factors: population density, human mobility, access to reliable water source, water storage practice etc. Community risks to dengue also dep...
The mosquitoes that spread dengue are active during the day. Lower the risk of getting dengue by protecting yourself from mosquito bites by using: 1. clothes that cover as much of your body as possible; 2. mosquito nets if sleeping during the day, ideally nets sprayed with insect repellent; 3. window screens; 4. mosquito repellents (containing DEET...
WHO responds to dengue in the following ways: 1. supports countries in the confirmation of outbreaks through its collaborating network of laboratories; 2. provides technical support and guidance to countries for the effective management of dengue outbreaks; 3. supports countries in improving their reporting systems and capture the true burden of th...
There are four closely related dengue viruses, which are called dengue serotypes. Although recovery from infection gives immunity from the same dengue serotype, it also increases the risk of severe dengue if people are later infected by a different serotype. Dengue is the most widely distributed mosquito-borne viral disease in the world.
Sep 20, 2019 · Infection with one serotype confers lifelong immunity against that serotype, but heterologus infection leads to severe dengue hemorrhagic fever due to antibody-dependent enhancement. Diagnosis of dengue infections is based mainly on serological detection of either antigen in acute cases or antibodies in both acute and chronic infection.
- Amudhan Murugesan, Mythreyee Manoharan
- 2020
- 10.1016/B978-0-12-819400-3.00016-8
Jan 24, 2019 · Humans can acquire symptomatic DENV infection more than once in a lifetime owing to the circulation of four antigenically distinct serotypes, DENV1–DENV4, which makes combating this disease...
- Ashley L St John, Ashley L St John, Abhay P S Rathore
- 2019
Sep 6, 2013 · Using novel mechanistic models to represent different hypothesized immune interactions between serotypes, we found strong evidence that infection with dengue provides substantial short-term cross-protection against other serotypes (approx. 1–3 years).
Aug 7, 2023 · A hotly contested hypothesis is that after a ‘primary’ infection with one serotype, ‘secondary’ infections by one or more of the other serotypes can precipitate ‘antibody-dependant enhancement’ (ADE). Resolution of this issue is hampered by the absence of a reliable animal model.
