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      • Dengue virus (DENV) has evolved various strategies to manipulate the innate immune responses of the host such as ‘hiding’ in the ultrastructure of the host, interfering with the signaling pathway through RNA modifications, inhibiting type 1 IFN production, as well as inhibiting STAT1 phosphorylation.
      www.ncbi.nlm.nih.gov › pmc › articles

      Innate and adaptive immune evasion by dengue virus - PMC

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  3. www.ncbi.nlm.nih.gov › pmc › articlesDengue virus and the host innate immune response - PMC

    Oct 10, 2018 · The innate immune response to DENV is not well characterized nor are the exact roles of the NS proteins in evading the immune response. The main innate immune response is type I IFN and the main evasion mechanism of the virus is to target against the type I IFN response.

  4. www.nature.com › articles › s41577/019/0123-xAdaptive immune responses to primary and secondary dengue ...

    Jan 24, 2019 · Here, we contrast the mechanisms initiating and sustaining adaptive immune responses during primary infection with the immune pathways that are pre-existing and reactivated during secondary...

    • Ashley L St John, Ashley L St John, Abhay P S Rathore
    • 2019

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  6. www.nature.com › scitable › contentImmune response to dengue infection | Learn Science at Scitable

    When someone is infected with dengue, the body's innate and adaptive immune responses work together to fight the virus. B cells from the immune system produce antibodies that recognize...

  7. www.tandfonline.com › doi › fullFull article: Dengue virus and the host innate immune response

    Oct 10, 2018 · The innate immune response to DENV is not well characterized nor are the exact roles of the NS proteins in evading the immune response. The main innate immune response is type I IFN and the main evasion mechanism of the virus is to target against the type I IFN response.

  8. www.frontiersin.org › journals › immunologyFrontiers | How Dengue Virus Circumvents Innate Immunity

    Dec 3, 2018 · DENV passively escapes from innate immunity surveillance and also actively subverts the innate immune system at multiple steps. DENV targets both RNA-triggered RLR–mitochondrial antiviral signaling protein (RLR–MAVS) and DNA-triggered cGAS–STING signaling to reduce IFN production in infected cells.

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