Penicillin (PCN or pen) is a group of antibiotics, derived originally from common moulds known as Penicillium moulds; which includes penicillin G (intravenous use), penicillin V (use by mouth), procaine penicillin, and benzathine penicillin (intramuscular use).
- Medical uses
The term "penicillin" was used originally for...
- Side effects
Common adverse drug reactions associated with use of the...
Penicillin inhibits activity of enzymes that are needed for...
- Medical uses
The Scottish physician Alexander Fleming was the first to suggest that a Penicillium mould must secrete an antibacterial substance, and the first to concentrate the active substance involved, which he named penicillin, the first modern antibiotic, in 1928.
Penicillin is a common antibiotic, used to treat bacterial infections. It was one of the first to be discovered, and worked well against staphylococci and streptococci. Many strains of bacteria are now resistant. Chemists keep changing part of its structure in the effort to keep it working against the bacteria.
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- Allergies and cross sensitivities
- Side effects in adults
- High doses
- Side effects from other medications
- In animals
The side effects of penicillin are bodily responses to penicillin and closely related antibiotics that do not relate directly to its effect on bacteria. A side effect is an effect that is not intended with normal dosaging. Some of these reactions are visible and some occur in the body's organs or blood. Penicillins are a widely used group of medications that are effective for the treatment of a wide variety of bacterial infections in human adults and children as well as other species. Some side
Many people have indicated that they have a side effect related to an allergic reaction to penicillin. It has been proposed that as many as 90% of those claiming to have an allergy to penicillin are able to take it and do not have a true allergy. Identifying an allergy to penicillin requires a hypersensitivity skin test, which diagnoses IgE-mediated immune responses caused by penicillin. This test is typically performed by an allergist who uses a skin-prick and intradermal injection of penicillo
Common adverse drug reactions associated with use of the penicillins include diarrhea, hypersensitivity, nausea, rash, neurotoxicity, urticaria, and superinfection. Infrequent adverse effects include fever, vomiting, erythema, dermatitis, angioedema, seizures, and pseudomembranous colitis.
When penicillin is used at high doses hypokalemia, metabolic acidosis, and hyperkalemia can occur. Developing hypernatremia after administering high doses of penicillin can be a serious side effect.
The side effects of penicillin can be altered by taking other medications at the same time. Taking oral contraceptives along with penicillin may lower the effects of the contraceptive. When probenecid is used concurrently with penicillin, kidney excretion of probenecid is decreased resulting in higher blood levels of penicillin in the circulation. In some instances, this would be an intended therapeutic effect. In other instances, this is an unintended side effect. Neomycin can lower the absorpt
Animals are often treated with antibiotics for infections they have developed. There are side effects of penicillin when it is used in animals. MRSA may develop in pets as a consequence of treatment. Nutritional deficiencies can develop in pets as a side effect. Destruction of the normal protective flora of beneficial bacteria can occur in dogs and horses. Dogs may have side effects that include: joint pain, loss of appetite, vomiting, flatulence, fungal infections and digestive problems. Like h
- Medical uses
- Adverse effects
- Mechanism of action
Phenoxymethylpenicillin, also known as penicillin V and penicillin VK, is an antibiotic useful for the treatment of a number of bacterial infections. Specifically it is used for the treatment of strep throat, otitis media, and cellulitis. It is also used to prevent rheumatic fever and to prevent infections following removal of the spleen. It is given by mouth. Side effects include diarrhea, nausea, and allergic reactions including anaphylaxis. It is not recommended in those with a history of pen
Specific uses for phenoxymethylpenicillin include: 1. Infections caused by Streptococcus pyogenes Tonsillitis Pharyngitis Skin infections 2. Anthrax 3. Lyme disease 4. Rheumatic fever 5. Streptococcal skin infections 6. Spleen disorders 7. Initial treatment for dental abscesses 8. Moderate-to-severe gingivitis 9. Avulsion injuries of teeth 10. Blood infection prophylaxis in children with sickle cell disease. Penicillin V is sometimes used in the treatment of odontogenic infections. It is less ac
Phenoxymethylpenicillin is usually well tolerated but may occasionally cause transient nausea, vomiting, epigastric distress, diarrhea, constipation, acidic smell to urine and black hairy tongue. A previous hypersensitivity reaction to any penicillin is a contraindication.
It exerts a bactericidal action against penicillin-sensitive microorganisms during the stage of active multiplication. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
Penicillin VK is a potassium salt of penicillin V.
Procaine benzylpenicillin also known as penicillin G procaine, is an antibiotic useful for the treatment of a number of bacterial infections. Specifically it is used for syphilis, anthrax, mouth infections, pneumonia, diphtheria, cellulitis, and animal bites. It is given by injection into a muscle.
Penicillin (ibland förkortat pc, PCN eller pen) är en grupp av antibiotika härledd från mögelsläktet Penicillium. Penicillinantibiotika är historiskt viktiga eftersom de är de första läkemedlen som var effektiva mot många tidigare allvarliga sjukdomar såsom syfilis - och stafylokockinfektioner.
A penicillin elnevezés (néha PCN a rövidítése) a β-laktám antibiotikumok egy csoportját jelenti, amelyeket az erre érzékeny, rendszerint Gram-pozitív baktériumok által okozott fertőzések kezelésére használnak. A „penicillin” nevet a csoport egyes tagjaira való hivatkozásként is használják.