Port St. Joe also has a community college that offers two year associate degrees. Port St. Joe has a library co-located with the senior citizens center, sheriff's office, courthouse, and animal shelter off State Road 71. The Florida Constitutional Convention of 1838 took place in St. Joe. There is a museum and monument commemorating this event.
The city is part of the Tampa-St. Petersburg-Clearwater, Florida Metropolitan Statistical Area which is a four-county area composed of roughly 3.1 million residents, making it the second largest metropolitan statistical area (MSA) in the state and the fourth largest in the Southeastern United States, behind Washington, D.C., Miami, and Atlanta.