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   What is a leukotriene receptor antagonist?

   • Leukotriene receptor antagonists are medications used to treat inflammatory respiratory conditions such as asthma and allergic rhinitis. Leukotriene receptor antagonists relieve the symptoms of asthma and allergic rhinitis by preventing leukotriene-induced inflammation, swelling of airways, excess mucus secretion and airway constriction.

   Leukotriene Receptor Antagonists: Drug Class, Uses, Side ... - RxList

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   How do leukotriene receptor antagonists work?

   • Contraction of the airway smooth muscles. Leukotriene receptor antagonists prevent inflammation by binding to the CysLT1 receptors and blocking cysteinyl leukotrienes from stimulating them. Leukotriene receptor antagonists block the activity of three types of cysteinyl leukotrienes, LTC4, LTD4 and LTE4.

   Leukotriene Receptor Antagonists: Drug Class, Uses, Side ... - RxList

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   What is zafirlukast a leukotriene antagonist?

   • Montelukast and zafirlukast are leukotriene receptor antagonists. They block the effects of leukotrienes. Zileuton is a leukotriene synthesis inhibitor. It prevents the body from making leukotrienes. How does someone take leukotriene receptor antagonists? Leukotriene modifiers are taken orally (by mouth), usually a tablet.

   Leukotriene Modifiers: Treatment & Definition - Cleveland Clinic

   my.clevelandclinic.org/health/drugs/14278-leukotriene-modifiers

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   Which leukotriene modifiers are used for allergic rhinitis?

   • Names of specific leukotriene modifiers include: Montelukast (Singulair®). Zafirlukast (Accolate®). Zileuton (Zyflo®). All three are used to treat asthma, but only montelukast is approved to treat allergic rhinitis. How do leukotriene modifiers work? Montelukast and zafirlukast are leukotriene receptor antagonists.

   Leukotriene Modifiers: Treatment & Definition - Cleveland Clinic

   my.clevelandclinic.org/health/drugs/14278-leukotriene-modifiers

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2. www.drugs.com › drug-class › leukotriene-modifiersList of Leukotriene modifiers (antileukotrienes) - Drugs.com

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   Leukotriene modifiers include two types of agents: Leukotriene-receptor antagonists, such as montelukast and zafirlukast, prevent leukotrienes from binding to their receptors. Leukotriene synthesis inhibitors, such as zileuton, block the enzyme, 5-lipoxygenase, which is necessary for the formation of leukotrienes.

3. my.clevelandclinic.org › health › drugsLeukotriene Modifiers: Treatment & Definition - Cleveland Clinic

   my.clevelandclinic.org › health › drugs

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   Leukotriene modifiers, also called leukotriene receptor antagonists, are a group of medications. They can help prevent breathing problems associated with allergies, asthma and chronic obstructive pulmonary disease. Examples include montelukast, zafirlukast and zileuton. What are leukotrienes?

4. www.ncbi.nlm.nih.gov › books › NBK554445Leukotriene Receptor Antagonists - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK554445

   Jun 4, 2023 · USA.gov. Montelukast and zafirlukast are cysteinyl leukotriene receptor antagonists indicated to prevent and treat chronic asthma. Leukotrienes are eicosanoid inflammatory mediators derived from arachidonic acid. Neither montelukast nor zafirlukast has a role as rescue medication during an acute asthmatic attack.

   • Author: Jaehwa Choi, Chaudhary Ehtsham Azmat
   • Published: 2023/06/04

   • Publish Year: 2020

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     Leukotrienes || structure , function and association with disease

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6. en.wikipedia.org › wiki › AntileukotrieneAntileukotriene - Wikipedia

   en.wikipedia.org › wiki › Antileukotriene

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   An antileukotriene, also known as leukotriene modifier and leukotriene receptor antagonist, is a medication which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist (cysteinyl leukotriene receptors) and consequently opposes the function of these inflammatory mediators ...

   • Synonyms: Leukotriene modifier; Leukotriene receptor antagonist

7. www.webmd.com › allergies › leukotrieneLeukotriene Modifiers and Allergies - WebMD

   www.webmd.com › allergies › leukotriene

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   Feb 20, 2024 · Leukotriene modifiers (leukotriene antagonists) are medicines used to manage allergic rhinitis or allergies, as well as prevent asthma. These novel drugs work by blocking the action...

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9. www.uptodate.com › contents › antileukotriene-agentsAntileukotriene agents in the management of asthma - UpToDate

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   Mar 21, 2024 · Studies using gene-deleted mice and selective receptor antagonists suggest that BLT 1 is the dominant receptor for LTB 4 in mediating chemotaxis of leukocytes and suggest that this receptor may be involved in facilitating eosinophilic airway pathology [ 15 ].

10. www.rxlist.com › leukotriene_receptor_antagonistsLeukotriene Receptor Antagonists: Drug Class, Uses, Side ...

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    Leukotriene receptor antagonists are medications used to treat inflammatory respiratory conditions such as asthma and allergic rhinitis. Leukotriene receptor antagonists relieve the symptoms of asthma and allergic rhinitis by preventing leukotriene-induced inflammation, swelling of airways, excess mucus secretion and airway constriction. Asthma ...