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    • Failed to stabilize and purify penicillin

      • Fleming, working with two young researchers, failed to stabilize and purify penicillin. However, he did point out that penicillin had clinical potential, both as a topical antiseptic and as an injectable antibiotic, if it could be isolated and purified.
      www.britannica.com › biography › Alexander-Fleming

      Alexander Fleming | Biography, Education, Discovery, Nobel ...

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  3. www.acs.org › education › whatischemistryAlexander Fleming Discovery and Development of Penicillin ...

    Fleming found that his "mold juice" was capable of killing a wide range of harmful bacteria, such as streptococcus, meningococcus and the diphtheria bacillus. He then set his assistants, Stuart Craddock and Frederick Ridley, the difficult task of isolating pure penicillin from the mold juice.

  4. en.wikipedia.org › wiki › Alexander_FlemingAlexander Fleming - Wikipedia

    Cecil George Paine, a pathologist at the Royal Infirmary in Sheffield and former student of Fleming, was the first to use penicillin successfully for medical treatment. [36] He cured eye infections ( conjunctivitis) of one adult and three infants ( neonatal conjunctivitis) on 25 November 1930.

    • 6 August 1881, Darvel, Ayrshire, Scotland

  5. www.britannica.com › biography › Alexander-FlemingAlexander Fleming | Biography, Education, Discovery, Nobel ...

    Mar 7, 2024 · In 1928 Alexander Fleming noticed that a culture plate of Staphylococcus aureus bacteria had become contaminated by a fungus. The mold, later identified as Penicillium notatum (now classified as P. chrysogenum ), had inhibited the growth of the bacteria.

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  7. www.ncbi.nlm.nih.gov › pmc › articlesAlexander Fleming (1881–1955): Discoverer of penicillin

    Initially, his research was not accepted, but Fleming continued undaunted and in 1922, he discovered lysozyme, an enzyme with weak antibacterial properties. History tells us that, while infected with a cold, Fleming transferred some of his nasopharyngeal mucus onto a Petri dish.

    • Siang Yong Tan, Yvonne Tatsumura
    • 10.11622/smedj.2015105
    • 2015
    • Singapore Med J. 2015 Jul; 56(7): 366-367.

  8. www.mayoclinicproceedings.org › article › S0025-6196The Yellow Brick Road to Penicillin: A Story of Serendipity

    The mouse-protection experiments with penicillin, an expansion of Fleming's work that had been initiated 11 years earlier, went smoothly. By late July in 1940, these experiments proved beyond a doubt the antibiotic potential of penicillin. The next step was trial injection of penicillin into humans.

    • John Warren Henderson
    • 1997

  9. stmuscholars.org › the-discovery-of-penicillin-byFrom Mold to Medicine: Alexander Fleming’s Penicillin Triumph

    Mar 15, 2024 · Callah Preti. In September of 1928, at St. Mary’s Hospital in London, a profound day in medical history occurred when Alexander Fleming noticed something peculiar on his Petri dish: a mold. Alexander stood silently in front of the Petri dish with mold streaks running across its translucent surface.

  10. sciencehistory.org › alexander-flemingAlexander Fleming | Science History Institute

    Fleming’s legendary discovery of penicillin occurred in 1928, while he was investigating staphylococcus, a common type of bacteria that causes boils and can also cause disastrous infections in patients with weakened immune systems.

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