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  1. Feb 24, 2015 · A major effort to evaluate the concordance between animal and human results is currently under way; two Working Groups were convened at IARC in 2012, and a systematic evaluation of the correspondence between human and animal data was undertaken (a report is not yet publicly available).

  2. genic Risk of Chemicals to Humansto IARC Monographs on the Evaluation of Carcino-genic Risks to Humans, in order to reflect the widened scope of the programme. The criteria established in 1971 to evaluate carcinogenic risk to humans were adopted by the working groups whose deliberations resulted in the first 16 volumes of the IARC Monographs ...

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  4. Preamble to the IARC Monographs (1991) 1. Background. In 1969, the International Agency for Research on Cancer (IARC) initiated a programme to evaluate the carcinogenic risk of chemicals to humans and to produce monographs on individual chemicals. The Monographs programme has since been expanded to include consideration of exposures to complex ...

  5. May 16, 2018 · For example, over 80 000 chemicals are currently registered for use in the USA alone, but only a small fraction have ever been evaluated for carcinogenicity. 15 Because of limited resources, no carcinogen evaluation programme is able to evaluate all agents of potential interest. Accordingly, the IARC Monographs give higher priority to ...

    • Dana Loomis, Neela Guha, Amy L Hall, Kurt Straif
    • 10.1136/oemed-2017-104944
    • 2018
    • Occup Environ Med. 2018 Aug; 75(8): 593-603.
  6. In 1988, the phrase ‘of chemicals’ was dropped from the title, which assumed its present form, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Through the Monographs programme, IARC seeks to identify the causes of human cancer. This is the first step in cancer prevention, which is needed as much today as when.

  7. Dec 1, 2023 · Read the IARC Monographs Q&A for answers to commonly asked questions on the evaluation process. Note: In September 2022, four additional individual Group 1 agents were created by splitting up some existing agent groupings because not all agents in the groups had the same cancer sites with sufficient and limited evidence for cancer in humans ...

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