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Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses. The spike protein assembles into trimers that form large structures, called spikes or peplomers, that project from the surface of the virion.
- Spike protein
Coronaviruses. Coronaviruses exhibit coronavirus spike...
- Coronavirus
The interaction of the coronavirus spike protein with its...
- Spike protein
Aug 3, 2020 · It is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The spike (S) protein of SARS-CoV-2, which plays a key role in the...
- Yuan Huang, Chan Yang, Xin feng Xu, Wei Xu, Shu wen Liu
- 2020
Oct 5, 2021 · The coronavirus virion is made up of the nucleocapsid (N), membrane (M), envelope (E) and spike (S) proteins, which are structural proteins (Fig. 1 ). The entry steps of the...
- Cody B Jackson, Cody B Jackson, Michael Farzan, Bing Chen, Bing Chen, Hyeryun Choe
- 2021
Sep 9, 2016 · The coronavirus spike protein is a multifunctional molecular machine that mediates coronavirus entry into host cells. It first binds to a receptor on the host cell surface through its S1 subunit and then fuses viral and host membranes through its S2 subunit.
Aug 2, 2021 · Abstract. Purpose. COVID-19 pandemic has emerged as a result of infection by the deadly pathogenic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causing enormous threats to humans. Coronaviruses are distinguished by a clove-like spike (S) protein, which plays a key role in viral pathogenesis, evolutions, and transmission.