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First described in 1910
- Roseola infantum was first described in 1910 and was named for its rose-colored rash [ 1 ]. The moniker sixth disease was designated to this syndrome as it was the sixth common childhood rash to be named, and the epithet exanthema subitem was also adopted, which translates to sudden rash [ 1 ].
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Jul 4, 2023 · Roseola infantum, also known as exanthema subitum or sixth disease, typically presents in children between six and 12 months of age; ninety percent of cases occur in children younger than two years. This condition is responsible for between 10 and 45 percent of febrile illness in infants.
- Tessa B. Mullins, Karthik Krishnamurthy
- 2023/07/04
History John Zahorsky MD wrote extensively on this disease in the early 20th century, his first formal presentation was to the St Louis Pediatric society in 1909 where he described 15 young children with the illness.
- Fever followed by rash
- Supportive care
- Before the age of three
Jan 18, 2024 · Roseola is a common viral exanthem of childhood, most frequently affecting infants and toddlers before age three. The syndrome is characterized by an abrupt onset of high fever, which, upon resolution, yields to a centrally located maculopapular rash that spreads peripherally.
Oct 9, 2020 · History. The classic roseola infantum patient is a 9- to 12-month-old infant in previously good health and who has an abrupt onset of high fever (40°C), which lasts for 3 days with...
I here note the oldest known description of roseola (exanthem subitum, “sixth disease”), predating by more than 100 years Zahorsky’s definitive description of roseola in JAMA in 1913. 1 I also point out that antiquity of human herpesvirus 6 (HHV6) 2 can be tracked via roseola.
Jun 12, 2023 · Overview. What is roseola? Roseola is a viral infection that mostly affects babies and young children, typically in the first two years of life. Roseola causes a sudden, high fever that lasts about three to four days. After the fever breaks, some children develop a rash that lasts two to four days.
Oct 9, 2020 · Background. Roseola is a common childhood disease. The cause is primary infection with human herpesvirus 6 (HHV-6). The classic presentation of roseola infantum is a 9- to 12-month-old infant...
