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What are Janeway lesions?
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What are Osler nodes & Janeway lesions?
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Janeway lesions are named after Edward Janeway (1841–1911), a prominent American physician, pathologist and contemporary of Sir William Osler, who initially described "peculiar skin lesions" in some people with endocarditis, in a paper published in 1899.
- Painless red flat papules on palms and soles.
- Infective endocarditis
- Sudden
Jan 16, 2021 · Janeway lesions are irregular, painless, erythematous or haemorrhagic macules, or papules commonly found on the palms and soles. The pathogenesis of Janeway lesions is still a controversial topic in the literature, but the main hypothesis is based on septic embolic events.
- Octavio Raul Jiménez Melo, María Jesús Pinilla Lozano, Elena Morte Romea, Alejandro Andrés Gracia
- 10.1093/ehjcr/ytaa490
- 2021
- 2021/01
Jun 1, 2021 · In 1899, Dr. Edward Janeway described painless lesions on the palms and soles in patients suffering from endocarditis. His objective in describing these lesions was a viable way for clinicians to differentiate endocarditis from another “malignant process” presenting with fever and weight loss.
- Adam J. Brown
- 2021
Jul 24, 2023 · Dr. William Osler first described Osler nodes in 1893 and Janeway lesions by Dr. Edward Janeway in 1899. The hypothesis is that Osler nodes and Janeway lesions share similar pathogenesis and arise from micro-emboli embedding in different anatomical sites.
- Krishan Parashar, Steven Daveluy
- 2023/07/24
- 2021
The lesions were first described by French Physicians as ‘Nodosites Cutanees Ephemeres’ meaning ‘ Cutaneous nodules of short duration’ and by Dr Mullen of Hamilton. Parkes Weber later suggested that they are known as Osler nodes in recognition of the fact that Sir William Osler (1849-1919) had "first called attention to their full ...
Feb 19, 2013 · Janeway lesions are named after Theodore Caldwell Janeway (1872–1917), an American professor of medicine. They are nontender, erythematous or hemorrhagic macular or nodular lesions on the palms or soles. 1 They are commonly seen in acute endocarditis.
Apr 18, 2019 · Janeway lesions are nontender hemorrhagic macules or papules located on palms, soles, and thenar and hypothenar eminences. Osler’s nodes are painful violaceous nodes typically found on fingers and toes. Traditionally, Janeway lesions have been attributed to septic emboli and Osler’s nodes described as an immunologic phenomenon.
