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1. pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine1-Phenylcyclohexylamine | C12H17N | CID 31862 - PubChem

   pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine

   Oct 14, 2021 · 1-Phenylcyclohexylamine | C12H17N | CID 31862 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2. analyticalsciencejournals.onlinelibrary.wiley.comPreparation and analytical characterization of 1‐(1 ...

   analyticalsciencejournals.onlinelibrary.wiley.com

   Apr 2, 2013 · Preparation and analytical characterization of 1‐ (1‐phenylcyclohexyl)piperidine (PCP) and 1‐ (1‐phenylcyclohexyl)pyrrolidine (PCPy) analogues - Wallach - 2014 - Drug Testing and Analysis - Wiley Online Library.

   • Author: Jason Wallach, Giorgia De Paoli, Adeboye Adejare, Simon D. Brandt
   • Cited By: 19

   • Publish Year: 2014
   • Published: 02 April 2013

3. People also ask

   What was the first arylcyclohexamine?

   • The first arylcyclohexamine to be described was 1- (1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP [ 1 ]. Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1- (1-phenylcyclohexyl)morpholine (PCMo).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   Do phenylcycloalkylamine analogs possess double digit nanomolar range IC 50 values?

   • In the current study, we screened new P 1 ′ position 1-phenylcycloalkylamine analogs to find non-acidic inhibitors that possess double-digit nanomolar range IC 50 values. An extensive structure–activity relationship study was performed with various amine derivatives at the P 1 ′ position.

   Structure-guided design and synthesis of P1′ position 1

   www.sciencedirect.com/science/article/pii/S0968089611005402

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   Are there any arylcyclohexamine analogues?

   • The only case series of other arylcyclohexamine analogues comes from the Swedish STRIDA project, which reported 59 cases of acute 3- and 4-MeO-PCP toxicity [ 101 ]; 86.4 % were male and the median age was 26 years.

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   Does chronic use of arylcyclohexamines affect working memory?

   • The subsequent reduction in dopaminergic activity seen with chronic use of arylcyclohexamines also plays a role in decreased working memory function of the prefrontal cortex [ 226 ].

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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4. webbook.nist.gov › cgi › cbookN-Phenylcyclohexylamine - NIST Chemistry WebBook

   webbook.nist.gov › cgi › cbook

   • Cached

   Feb 6, 2010 · Molecular weight: 175.2701. IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11 (8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2. IUPAC Standard InChIKey: TXTHKGMZDDTZFD-UHFFFAOYSA-N. CAS Registry Number: 1821-36-9. Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file.

5. www.sciencedirect.com › science › articleStructure-guided design and synthesis of - ScienceDirect

   www.sciencedirect.com › science › article

   Sep 1, 2011 · An extensive structure–activity relationship study was performed with various amine derivatives at the P 1 ′ position. The most potent inhibitor of this pentapeptide series, KMI-1830, possessing 1-phenylcyclopentylamine at the P 1 ′ position had an IC 50 value of 11.6 nM against BACE1 in vitro enzymatic assay.

   • Author: Harichandra D. Tagad, Yoshio Hamada, Jeffrey-Tri Nguyen, Koushi Hidaka, Takashi Hamada, Youhei Sohma...

   • Publish Year: 2011

6. www.semanticscholar.org › paper › THE-SYNTHESIS-OFTHE SYNTHESIS OF PHENCYCLIDINE AND OTHER 1 ...

   www.semanticscholar.org › paper › THE-SYNTHESIS-OF

   A series of phencyclidine homologs was synthesized by reductive cyclization of substituted ω-chlorine-substituted l-N- [l- (p-hydroxybenzyl)cyclohexyl]amides with LiAlH4 by characterized and tested for neurotropic activity. Expand. 1. Synthesis and biological activity of cyclohexylamine derivatives. V. A. Glushkov O. S. P’yankova. +4 authors.

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8. link.springer.com › referenceworkentry › 10Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com › referenceworkentry › 10

   • Cached

   Jan 1, 2016 · The first arylcyclohexamine to be described was 1- (1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP [ 1 ]. Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1- (1-phenylcyclohexyl)morpholine (PCMo).

9. www.semanticscholar.org › paper › Synthesis-andSynthesis and anticonvulsant activity of 1 ... - Semantic Scholar

   www.semanticscholar.org › paper › Synthesis-and

   Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues. | Semantic Scholar. DOI: 10.1021/JM00167A027. Corpus ID: 11849936. Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues. A. Thurkauf, B. de Costa, +4 authors. M. Rogawski. Published in Journal of Medicinal… 1 May 1990. Chemistry, Medicine. TLDR.