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1. • • His contributions to science and humankind were recognized with almost every prize imaginable, including the Nobel Prize in 1984, the Copley Medal of the Royal Society, the first MRC Millennium Prize, and a Companion of Honour for services to molecular biology.
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     RETROSPECTIVE: César Milstein (1927-2002) | Science

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   Who was César Milstein?

   • Credit: Photo credit: Tim Springer César Milstein was born in 1927 at Bahia Blanca, Argentina, to immigrants from Russia involved in the secular, intellectual Jewish culture of the time. César was an adventurous youth who went to college in Buenos Aires, where he majored in chemistry and was active in politics.

   César Milstein, the father of modern immunology - Nature

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   Why did César Milstein study antibody diversity?

   • César Milstein began to study antibody diversity at a time when almost nothing was known about its molecular and genetic basis. As a logical step in that work, with Georges Köhler he devised the hybridoma technique for fusing cancer cells with antibody-producing cells to produce homogeneous (monoclonal) antibodies.

   César Milstein (1927–2002) | Nature

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   Where did César Milstein grow up?

   • The son of Jewish immigrants, César Milstein grew up in Bahía Blanca, a port town located by the Atlantic ocean some 500 miles south of Buenos Aires. Jews had begun to settle in Bahía Blanca from around 1900, many of them coming from central and eastern Europe.

   The Story of César Milstein and Monoclonal Antibodies

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   Who were César Milstein and Georges Köhler?

   • César Milstein and Georges Köhler together in 1984, the year they were awarded the Nobel Prize in physiology or medicine, jointly with Niels Jerne. Credit: Photo reproduced courtesy of the MRC Laboratory of Molecular Biology, Cambridge, UK.

   The birth of monoclonal antibodies | Nature Immunology

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3. www.nature.com › articles › ni0602-501César Milstein, the father of modern immunology | Nature ...

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   Jun 1, 2002 · 10 Citations. 3 Altmetric. Metrics. In memoriam: César Milstein, who with the late Georges Köhler invented monoclonal antibodies, died on 24 March 2002. Their invention sprang from basic...

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   • César Milstein (1927–2002)

     Obituary. César Milstein (1927–2002) Klaus Rajewsky. Nature...

4. www.aai.org › Nobel-Laureates › CesarMilsteinThe American Association of Immunologists - César Milstein

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   César Milstein was awarded the 1984 Nobel Prize in Physiology or Medicine jointly with his former postdoctoral fellow Georges J. F. Köhler (AAI '85) and theoretician Niels Jerne (AAI '73). Milstein and Köhler won the prize for developing the hybridoma method of producing monoclonal antibodies.

5. www.whatisbiotechnology.org › indexThe Story of César Milstein and Monoclonal Antibodies

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   Milstein's father, Lazaro, was born in a village in the Ukraine and migrated to Argentina in 1913 at the age of 14 with his aged aunt and uncle. For many years he lived in Jewish settlements near Bahía Blanca trying his hand at different trades, including farm labour, carpentry and railway work. During this time he taught himself Spanish and ...

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     César Milstein describes the moment he was informed of the Nobel Prize

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     César Milstein: Premio Nobel de Medicina - Canal Encuentro HD

     Nov 10, 2016

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     The Ballad of Cesar Milstein

     Jul 4, 2011

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7. www.nature.com › articles › niThe birth of monoclonal antibodies | Nature Immunology

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   Dec 2, 2016 · 11 Citations. 29 Altmetric. Metrics. On 7 August 1975, Nature published a three-page report by César Milstein and Georges J. F. Köhler describing a method for generating large amounts of...

   • Author: Olive Leavy

   • Publish Year: 2016

8. www.oxforddnb.com › display › 10Milstein, César (1927–2002), molecular biologist and ...

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   The more detailed structure of antibodies was a key topic of the time and Milstein soon became a leading figure in the field. His first publication was on the structure of the di-sulphide bonds of an antibody ‘light’ chain.

9. www.science.org › doi › 10RETROSPECTIVE: César Milstein (1927-2002) | Science

   www.science.org › doi › 10

   May 17, 2002 · Milstein decided to work on a hot new topic—the molecular basis of antibody diversity and specificity. His early interest in somatic hypermutation as a mechanism for generating antibody diversity was the impetus that led him to invent monoclonal antibodies.