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  2. Feb 10, 2024 · In most cases, dementia is not inherited; however, this depends on the type of dementia. Discover what causes dementia and when genetics play a role.

    • Overview
    • Can dementia be passed down in families?
    • How likely are you to get dementia if it runs in your family?
    • How is dementia passed genetically?
    • How do you avoid dementia if it runs in your family?
    • Takeaway

    Usually, genetics can only increase your risk of developing dementia but not directly cause it. But there is a rare type that is passed down in families.

    About 55 million people worldwide have dementia. There are several types of this common degenerative condition, and most are linked to aging.

    There are multiple risk factors for dementia, including family history. Many families carry a gene that can increase the risk of developing dementia — but not a gene that directly causes dementia.

    You’re more likely to have genes that increase your risk of dementia if you have a family member who developed dementia before they turned 60 years old, or if you have a parent or sibling who developed dementia.

    The risk of dementia can run in families. However, it’s rare for dementia itself to be passed down genetically. This might sound confusing but it’s because of the different types of genes that can lead to conditions such as dementia.

    There are four genes known to increase your risk of developing dementia, and these genes do run in families. But this doesn’t mean dementia is an inherited condition. Many people with these genes never develop dementia, and many people without these genes do develop dementia.

    Genetic testing can help you look at possible risks in your family. If people in your family have any form of dementia, looking at how many people have it and the ages they developed it can help you assess risk.

    For instance, although anyone can develop dementia, the risk is known to be higher if you have:

    •a family member who developed dementia when they were younger than age 60

    •a parent who developed dementia

    •a sibling who developed dementia

    It’s also a good idea to talk with a doctor about your possible risk of developing dementia. Family history can sometimes give you an idea of risk, but it’s not a reliable indicator.

    Some genes and gene abnormalities make it more likely that you’ll develop a condition, but don’t necessarily mean you will get that condition. These genes don’t cause a condition, they just put you at higher risk.

    One important gene that increases the risk of dementia is called Apolipoprotein E. This gene is carried on chromosome 19. Everyone carries two of these genes in pairs, one inherited from each parent.

    It’s a good idea to talk with a doctor if you’re concerned about your dementia risk. You can also make lifestyle adjustments at home.

    Some lifestyle changes may help you live a healthier life and even lower your overall risk of developing dementia, even if you have a genetic risk.

    This includes:

    •getting adequate sleep every night

    •quitting smoking

    •getting at least 150 minutes of exercise each week

    Having a family member with dementia can increase your risk of developing dementia. The risk goes up if your family member developed dementia before they turned 60 years old or if the family member is a parent or sibling.

    There are also genes that make it more likely that someone will get dementia that can be passed along in families. However, having these genes does not mean you will develop dementia. Many people with these genes never get dementia, while many without them do develop the condition.

    A rare type of dementia called familial Alzheimer’s disease is caused by a gene that is passed down in families. This gene directly causes dementia and is inherited in family lines.

    If you’re concerned about dementia in your family, genetic testing can show you if you have any genes known to increase the risk.

  3. Many people affected by dementia are concerned that they may inherit or pass on dementia. The majority of dementia is not inherited by children and grandchildren . In rarer types of dementia there may be a strong genetic link, but these are only a tiny proportion of overall cases of dementia.

  4. Apr 30, 2024 · In fact, more than 99 percent of cases are not inherited, meaning that even if your parents or grandparents suffer from Alzheimers, you will not necessarily be at an increased risk. So, if inherited genetics is not the most important risk factor, what is?

  5. Medical research seems to suggest that it is very unlikely that dementia can be passed on through our DNA. But in rare cases, some diseases that lead to dementia can be passed on through our DNA. But it is still extremly rare that if a family member such as a parent or grandparent has developed one of the many different kinds of dementia , that ...

  6. May 8, 2023 · In most cases, dementia is not strictly hereditary, but the disease underlying dementia is usually caused by a combination of various genetic and environmental factors. However, there are a few cases of familial dementia, where dementia is inherited and caused by genetic mutations.

  7. Generally, if you are diagnosed with eFAD, then one of your parents will also have had it if he or she lived long enough, and your siblings and your children may have a 50-50 chance of having inherited it. Very rarely, eFAD can make a first-time appearance in a family through a new genetic mutation.

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