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In this area, Affymetrix was focused on oligonucleotide microarrays, which could be used to address the presence of genes through detection of specific corresponding segments of mRNA. The single-use chips could be used to analyze thousands of genes in a single assay.
Microarray technology enables the flexible throughput analysis of genotyping, chromosome copy number variations and gene expression. It can be applied to various applications such as predictive genomics, reproductive health and oncology research.
The Affymetrix GeneChip system is a commercial microarray platform that allows high-throughput genotyping for human samples with as little as 250 ng of genomic DNA.
Oct 18, 2023 · In 2002, Affymetrix™ GeneChip™ microarrays harnessed this sequence data to offer over 500,000 unique probes per chip, enabling researchers to instantly access gene expression information for over 33,000 genes (Affymetrix Inc., 2003).
Jun 18, 2021 · We examined 28 arrays (10 from Affymetrix and 18 from Illumina), including the newest generation of genotyping arrays (Table 1). To examine the general characteristics of the included arrays, we...
Jun 17, 2008 · The present study implements seven methods commonly used in the literature to calculate expression indices from Affymetrix microarray gene expression data, which was collected from a well-designed genome-wide microarray hybridization experiment with eight genetically divergent barley cultivars.
Sep 6, 2023 · In this article, we walk through an end-to-end Affymetrix microarray differential expression workflow using Bioconductor packages. This workflow is directly applicable to current “Gene” type arrays, e.g. the HuGene or MoGene arrays, but can easily be adapted to similar platforms.
