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1. • • Treatment with β-blockers is the main strategy for managing patients with heart failure and reduced ejection fraction because of their ability to reverse the neurohumoral effects of the sympathetic nervous system, with consequent prognostic and symptomatic benefits.
     www.ncbi.nlm.nih.gov › pmc › articles

     The Use of β-Blockers in Heart Failure with Reduced Ejection ...

2. People also ask

   Do beta blockers work in a failing heart?

   • Unlike the well-demonstrated beneficial effects of beta blockers (BBs) in previous HF trials, the effects of ABs remain controversial, especially in the failing heart where the quantity and function of cardiac alpha-adrenergic receptors are augmented and maintained.

   Are Alpha-Adrenergic Receptor Antagonists ... - JACC: Heart Failure

   www.jacc.org/doi/10.1016/j.jchf.2018.07.013

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   Do alpha blockers increase risk of hypertension in older patients?

   • The 2 clinical situations usually exist in combination among older patients. Alpha blockers (ABs), when used for the treatment of hypertension, have been associated with increased risk of HF, which has raised some concerns (1).

   Are Alpha-Adrenergic Receptor Antagonists ... - JACC: Heart Failure

   www.jacc.org/doi/10.1016/j.jchf.2018.07.013

   See all results for this question

   What is the role of -blockers in the treatment of heart failure?

   • Potential Role of α-Blockers in Treatment of Heart Failure Cardiac insult, which may have any number of causes, may cause deterioration of heart function, which in turn may cause activation of the numerous neurohumoral systems including the sympathetic nervous system through α- and β-adrenergic receptors.

   Are Alpha-Adrenergic Receptor Antagonists ... - JACC: Heart Failure

   www.jacc.org/doi/10.1016/j.jchf.2018.07.013

   See all results for this question

3. www.ahajournals.org › doi › 102022 AHA/ACC/HFSA Guideline for the Management of Heart Failure

   www.ahajournals.org › doi › 10

   Apr 1, 2022 · Heart failure remains a leading cause of morbidity and mortality globally. The 2022 heart failure guideline provides recommendations based on contemporary evidence for the treatment of these patients.

   • Home | AHA/ASA Journals

     Home | AHA/ASA Journals

   • Treatment of Chronic Heart Failure With β-Adrenergic Receptor ...

     β-Adrenergic blocking agents are now considered first-line...

4. pubmed.ncbi.nlm.nih.gov › 30316936Safety of Alpha-Adrenergic Receptor Antagonists in Heart Failure

   pubmed.ncbi.nlm.nih.gov › 30316936

   Objectives: This study evaluated whether alpha-blocker (AB) use following an admission for heart failure (HF) was associated with an increased risk of HF readmission or death.

   • Author: Cynthia A. Jackevicius, Zunera Ghaznavi, Lingyun Lu, Alberta L. Warner

   • Publish Year: 2018

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6. www.ncbi.nlm.nih.gov › pmc › articlesThe Use of β-Blockers in Heart Failure with Reduced Ejection ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Aug 24, 2021 · Treatment with β-blockers is the main strategy for managing patients with heart failure and reduced ejection fraction because of their ability to reverse the neurohumoral effects of the sympathetic nervous system, with consequent prognostic and symptomatic benefits.

   • Author: Daniele Masarone, Maria Luigia Martucci, Vittoria Errigo, Giuseppe Pacileo

   • Publish Year: 2021

7. www.jacc.org › doi › 10Are Alpha-Adrenergic Receptor ... - JACC: Heart Failure

   www.jacc.org › doi › 10

   In the complex interplay between heart and neurohumoral systems during heart failure, chronic and maladaptive processes (red arrow) can be inhibited (black bars) by ACE inhibitors, angiotensin II receptor blockers, β-blockers, aldosterone antagonists, and so forth.

   • Author: Seung Yong Shin, Gregory Y.H. Lip

   • Publish Year: 2018

8. www.ncbi.nlm.nih.gov › pmc › articlesEffectiveness and safety of four different beta‐blockers in ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jan 6, 2023 · Initiation with a very low dose of β blockers and titration to the tolerated dose is recommended as the cornerstone in the treatment of chronic heart failure (CHF) with reduced ejection fraction, but which β blocker has the superiority over others remains unclear. 1 It is necessary to perform an all‐sided pooled analysis that can exploit the tot...

9. www.ccjm.org › content › ccjomAlpha-blockers and congestive heart failure: Early ...

   www.ccjm.org › content › ccjom

   ABSTRACT. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) is a large, randomized double-blind study comparing four antihypertensive agents (chlorthalidone, doxazosin, amlodipine, and lisinopril) in hypertensive patients older than 55 years.