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    • Epithelial cells of the vagina

      • Clue cells are epithelial cells of the vagina that get their distinctive stippled appearance by being covered with bacteria.
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  1. en.wikipedia.org › wiki › Clue_cellClue cell - Wikipedia

    Clue cells are epithelial cells of the vagina that get their distinctive stippled appearance by being covered with bacteria. The etymology behind the term "clue" cell derives from the original research article from Gardner and Dukes describing the characteristic cells.

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    • ◉ Diagnosis of Clue Cells
    • ◉ What Does It Mean If You Have Clue Cells ?
    • ◉ What Are Clue Cells Caused by?
    • ◉ Is It Normal to Have Some Clue Cells ?

    To detect clue cells, a healthcare provider will perform a vaginal exam and collect a sample of vaginal discharge using a sterile swab for microscopy observation. 1. Place the sample on a clean microscope slide by rolling the swab back and forth. 2. Let it dry, then perform a Gram stain. 3. Examine the slide under a microscope using oil immersion a...

    Normally, the vagina contains a balance of different types of bacteria that help maintain a healthy environment. The presence of clue cells in a sample of vaginal secretions indicates an abnormal overgrowth of certain types of bacteria and depletion of protective bacteria such as lactobacillus, this is a hallmark of bacterial vaginosis, a common va...

    Gardnerella vaginalis is a type of bacteria that is commonly associated with bacterial vaginosis. It is a Gram-variable bacilli or coccobacilli ; catalase and oxidase negative; sodium hippurate hydrolysis positive; acid production from glucose, maltose, and sucrose (variable)

    It may indicate the presence of BV. However, the interpretation should be made in conjunction with other clinical and laboratory findings, as the presence of clue cells alone is not sufficient to diagnose BV.

  3. Dec 27, 2023 · Clue cells are specialized vaginal epithelial cells that appear stippled or granulated due to being covered with numerous bacteria. Meanwhile, these cells are a critical diagnostic feature in gynecology, particularly for diagnosing bacterial vaginosis (BV), a common vaginal infection.

  4. Dec 7, 2023 · Bacterial vaginosis (BV) is a clinical condition characterized by a shift in vaginal microbiota away from Lactobacillus species toward more diverse bacterial species, including facultative anaerobes. The altered microbiome causes a rise in vaginal pH and symptoms that range from none to very bothersome (eg, abnormal vaginal discharge and odor).

  5. A clue cell is a type of cell found in the vagina, an epithelial cell, that when examined under a microscope is found to have a cluster of bacteria attached to it. 1,2 Clue cells are distinctive in appearance, as they are covered in bacteria and what’s known as a bacterial biofilm .

  6. Clue cells are vaginal epithelial cells that have a stippled appearance due to adherent coccobacilli ( Figure 1). The edges of the cells are obscured and appear fuzzy compared with the...

  7. Oct 2, 2006 · Clue cells are squamous cells covered by coccobacilli with extension to the cell edges (velvety coat or shaggy appearance) The entire cell does not need to be covered. Lactobacilli and inflammatory cells are absent, unless there is another infectious process.

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