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Jan 17, 2014 · Tolerance is the prevention of an immune response against a particular antigen. For instance, the immune system is generally tolerant of self-antigens, so it does not usually attack the body's own cells, tissues, and organs.
Immune tolerance is known as the state of an active, highly regulated unresponsiveness of the immune system to self-antigens or against a particular antigen that can induce an immune response in the body.
Immune tolerance, also known as immunological tolerance or immunotolerance, refers to the immune system's state of unresponsiveness to substances or tissues that would otherwise trigger an immune response.
Dec 8, 2023 · Immune tolerance represents the long-term or permanent constraint of potentially harmful immune responses towards innocuous stimuli. This regulation is achieved through both central and peripheral immune mechanisms targeting T and B lymphocytes.
Immune tolerance is defined as nonresponsiveness of the adaptive immune system to antigens. Immune mechanisms preventing inappropriate immune reactivity to innocuous antigens include deletion of reactive lymphocytes and generation of regulatory T (Treg) cells. The normal response to food antigens is the generation of antigen-specific Treg cells.
Immunological tolerance is the state of lack of immunological responsiveness to an antigen. Tolerance to self-antigens is a key physiological feature of a normal immune system. Failure of tolerance to self results in autoimmunity.
Jul 26, 2022 · I summarize how diverse mechanisms may contribute to self‐tolerance, and how an appreciation of their interdependence is necessary to understand how they collectively provide the imperfect degree of tolerance achieved.
Oct 31, 2023 · The acquired ability to prevent an unnecessary or harmful immune response to a detected foreign substance known not to cause disease or to self-antigens is described as immune tolerance.
Nov 21, 2023 · Immunological tolerance is vital to the health and well-being of any organism with an adaptive immune system. Immune tolerance allows the culling of lymphocytes that have receptors with a high...
Jan 3, 2017 · This defence strategy, known as disease tolerance, relies on tissue damage control mechanisms that prevent the deleterious effects of pathogens and that uncouples immune-driven resistance...
