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- Dame Iris Murdoch was diagnosed with Alzheimer's disease at the age of 76, shortly after the publication of her final novel in 1995. Neuropsychological assessments in 1997 showed that she was losing a range of cognitive abilities including arithmetic, spelling, and word production.
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Dec 1, 2004 · Dame Iris Murdoch was diagnosed with Alzheimer's disease at the age of 76, shortly after the publication of her final novel in 1995. Neuropsychological assessments in 1997 showed that she was losing a range of cognitive abilities including arithmetic, spelling, and word production.
- Introduction
- Material and Methods
- Results
- Discussion
- Author Notes
The neuropsychological deficits attributable to neocortical involvement in the early stages of Alzheimer's disease have been documented extensively, allowing important clinical subgroups to be identified. These include patients with deficits in early visual processing, spatial skills and various components of language, implicating occipital, bi-par...
The complete texts of I.M.'s first and final published works—Under the Net (1954) and Jackson's Dilemma (1995)—were converted to digital format using commercial optical character recognition software. The same procedure was performed on the first 100 pages of The Sea, The Sea(1978), a book written at the height of her literary career, and widely re...
Overall differences between books
Table 2 summarizes the general characteristics of the novels and illustrates that, although differences are apparent at this very broad level, there is no consistent pattern: the first book is subdivided into more chapters than either of the two later works, while the middle work is far and away the longest of the three; the proportion of text that is devoted to dialogue rather than narrative is largest in the final novel and smallest in the mid-career work; more characters (defined as unique...
Comment
The syntactic analyses reported above have produced conflicting results, which reflect a number of limitations of the methods used. The selection of sentences for manual analysis was imperfect because the sentences chosen represent consecutive elements of larger passages, with their own higher order structure, of which the length of the constituent sentences may have been a reflection. On the other hand, although the designation of a sentence as consisting of all the words between successive...
Lexical differences
Differences at the level of individual lexical variables were sought by comparing the distribution of values of these variables associated with the word samples that were drawn randomly from each of the three books. Values of frequency (Kucera and Francis norms), familiarity, age of acquisition and concreteness were assigned to as many words as possible using the MRC online psycholinguistic database. Length was computed automatically for every word. Not surprisingly, the resulting data set co...
Through a systematic comparison of three texts, we have attempted to establish, at a number of different levels of analysis, the ways in which a prominent writer's literary output might have been affected by the earliest stages of post- mortem-proven Alzheimer's disease. The first of these texts—Under the Net—was composed while the subject (I.M.) w...
1Institute of Cognitive Neuroscience, London, 2Defence Services Medical Rehabilitation Unit, Headley Court, Epsom, Surrey and 3MRC Cognition and Brain Science Unit, Cambridge, UK
- Peter Garrard, Lisa M. Maloney, John R. Hodges, Karalyn Patterson
- 2004
Iris Murdoch was diagnosed with Alzheimer's disease in 1997 and died in 1999 in Oxford. There is a bench dedicated to her in the grounds of Lady Margaret Hall, Oxford, where she used to enjoy walking.
Dec 1, 2004 · A vocabulary analysis of the final book by British novelist Iris Murdoch reveals the early stages of the Alzheimer's disease that killed her, neuroscientists have found. The discovery shows...
- Michael Hopkin
- 2004
Feb 21, 2017 · Two years after Jackson’s Dilemma was published, Murdoch saw a neurologist who diagnosed her with Alzheimer’s disease.
Dec 2, 2004 · Researchers in London who analyzed the final novel by author Iris Murdoch have detected signs of Alzheimer's disease in the book's language. Murdoch wrote Jackson's Dilemma just before...
Feb 9, 1999 · Iris Murdoch, a prodigiously inventive and idiosyncratic British writer whose 26 novels offered lively plots, complex characters and intellectual speculation, died yesterday at a nursing home...
