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  1. May 15, 2024 · Laboratory diagnosis of Lyme disease relies on a blood test that detects antibodies to the Lyme bacteria. It can take several weeks after infection for the immune system to make enough antibodies to be detected by the test.

  2. The CDC recommends two-step testing, sometimes referred to as a two-tiered test, for Lyme disease. You will need to go to a lab to have blood drawn. It takes a few days to get results. If the first test comes back positive or unclear, the lab will do the second blood test.

  3. Jun 30, 2023 · The tests that look for Lyme disease arent foolproof, so your doctor may decide to start you on treatment based on your symptoms and the likelihood you’ve been exposed to ticks.

  4. Feb 10, 2023 · If you live where Lyme disease is common, the rash might be enough for a diagnosis. A diagnosis usually depends on the following: A review of all signs and symptoms. A history of known or possible exposure to ticks. Blood tests to find disease-fighting antibodies to the bacteria.

  5. May 15, 2024 · Key points. Laboratory diagnosis of Lyme disease relies on serologic testing for antibodies to Borrelia burgdorferi. CDC recommends a two-step serologic testing process using FDA-cleared assays. Serologic assays may be falsely negative during the first 4-6 weeks after infection.

  6. May 31, 2024 · The CDC recommends that doctors first order an enzyme-linked immunosorbent assay (ELISA) test to screen for Lyme disease and then confirm Lyme disease with a Western blot test, which checks...

  7. Lyme disease tests look for signs of infection in a sample of your blood or cerebrospinal fluid (CSF). CSF is a clear liquid that flows in and around your brain and spinal cord. The test checks your sample for antibodies that your immune system makes to fight the bacteria that cause Lyme disease.

  8. On July 29, 2019, the FDA cleared several Lyme disease serologic assays for use based on a modified two-test methodology, allowing a sensitive enzyme immunoassay (EIA) or immunofluorescence assay first test to be followed by a second EIA in place of a western immunoblot assay.

  9. Feb 10, 2023 · Lyme disease is an illness caused by borrelia bacteria. Humans usually get Lyme disease from the bite of a tick carrying the bacteria. Ticks that can carry borrelia bacteria live throughout most of the United States. But Lyme disease is most common in the upper Midwest and the northeastern and mid-Atlantic states.

  10. Clinical Testing and Diagnosis for Lyme Disease. CDC recommends a two-step serologic testing process for Lyme disease using FDA-cleared assays.

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