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  1. Feb 17, 2023 · This investigational multivalent protein subunit vaccine uses an established mechanism of action for a Lyme disease vaccine that targets the outer surface protein A (OspA) of Borrelia burgdorferi, the bacteria that cause Lyme disease.

  2. Dec 4, 2023 · There are currently no approved human vaccines for Lyme disease, and VLA15 is the most advanced Lyme disease vaccine candidate currently in clinical development, with two Phase 3 trials in progress.

  3. Aug 9, 2022 · Forbidding Forecast For Lyme Disease In The Northeast. The new vaccine is called VLA15, and as of this week, it's now in the third phase of a clinical study in humans. It was created by...

  4. Aug 10, 2022 · Health. Major test of 1st potential Lyme disease vaccine in 20 years begins in U.S., Europe. No safety issues, good immune response reported in early-stage studies, vaccine makers say. The...

  5. Apr 29, 2021 · As of October 2022, VLA15 was the sole active vaccine candidate program in clinical development aimed at preventing the spread of the disease. 11 Preclinical experiments in animal models found that the vaccine candidate was able to effectively prevent transmission of North American and European Borrelia strains from infected Ixodes ticks. 11 If ...

  6. Sep 19, 2023 · PHILADELPHIA— An experimental mRNA vaccine provides protection in preclinical animal models against infection from Borrelia burgdorferi, the bacteria that causes Lyme disease, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

  7. Jun 17, 2021 · Currently, there is no human vaccine for Lyme diseaseeven though more than two decades ago, people could get a safe and effective preventative shot similar to Fawn’s. Now, thanks to potent...

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