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  2. Navigate sepsis diagnosis with the SIRS, Sepsis, and Septic Shock Criteria Calculator. Elevate care in critical conditions with our SIRS, Sepsis, and Septic Shock Calculator.

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  2. A tool to define the severity of sepsis and septic shock based on clinical signs, symptoms, and laboratory data. Learn the history, pearls, pitfalls, and updates of the SIRS criteria from the creator and other sources.

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    Symptoms of sepsis

    Symptoms of sepsis may include:

    Symptoms of septic shock

    Sepsis may progress to septic shock. Septic shock is a severe drop in blood pressure. Progression to septic shock raises the risk of death. Symptoms of septic shock include:

    Any infection could lead to sepsis. Go to a health care provider if you have symptoms of sepsis or an infection or wound that isn't getting better.

    Symptoms such as confusion or fast breathing need emergency care.

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    Any type of infection can lead to sepsis. This includes bacterial, viral or fungal infections. Those that more commonly cause sepsis include infections of:

    •Lungs, such as pneumonia.

    •Kidney, bladder and other parts of the urinary system.

    •Digestive system.

    •Bloodstream.

    •Catheter sites.

    Some factors that increase the risk infection will lead to sepsis include:

    •People over age 65.

    •Infancy.

    •People with lower immune response, such as those being treated for cancer or people with human immunodeficiency virus (HIV).

    •People with chronic diseases, such as diabetes, kidney disease or chronic obstructive pulmonary disease (COPD).

    •Admission to intensive care unit or longer hospital stays.

    As sepsis worsens, vital organs, such as the brain, heart and kidneys, don't get as much blood as they should. Sepsis may cause atypical blood clotting. The resulting small clots or burst blood vessels may damage or destroy tissues.

    Most people recover from mild sepsis, but the mortality rate for septic shock is about 30% to 40%. Also, an episode of severe sepsis raises the risk for future infections.

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    By Mayo Clinic Staff

    Feb 10, 2023

    1.Forrester JD. Sepsis and septic shock. Merck Manual Professional Version. https://www.merckmanuals.com/professional/critical-care-medicine/sepsis-and-septic-shock/sepsis-and-septic-shock. Accessed Nov. 19, 2022.

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    Sepsis is a serious condition in which the body responds improperly to an infection. Learn about the symptoms, causes, risk factors and complications of sepsis and septic shock.

  3. Apr 1, 2020 · Learn about the revised definition of sepsis and septic shock, the Sequential Organ Failure Assessment (SOFA) and quick SOFA tools, and the sepsis bundle of interventions. The article also covers the epidemiology, pathophysiology, and complications of sepsis.

  4. Feb 13, 2024 · Learn how to diagnose and treat sepsis and septic shock in adults, based on 2021 guidelines and evidence. Find out the definitions, pathophysiology, investigations, and interventions for sepsis, as well as the role of fluids, antibiotics, vasopressors, and more.

  5. Sepsis: two Systemic Inflammatory Response syndrome (SIRS) criteria plus evidence of infection. Severe sepsis: Sepsis with evidence of organ dysfunction. Septic shock: Sepsis with persistent hypotension, despite fluid resuscitation. Go to: Key Points. Recognition of sepsis.

    • 2023
  6. Dec 10, 2021 · The guidelines provide evidence-based recommendations for the diagnosis, management, and prevention of sepsis and septic shock in adult patients. They include criteria for sepsis, septic shock, and organ dysfunction, as well as strategies for resuscitation, antibiotics, fluids, and more.

  7. Learn about the causes, pathophysiology, symptoms, diagnosis, and treatment of sepsis and septic shock, a life-threatening organ dysfunction caused by infection. Find out the latest definitions, criteria, and prognosis of sepsis and septic shock.

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    Navigate sepsis diagnosis with the SIRS, Sepsis, and Septic Shock Criteria Calculator. Elevate care in critical conditions with our SIRS, Sepsis, and Septic Shock Calculator.

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