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  2. Rx To Help Reduce Heavy Menstrual Bleeding Due To Uterine Fibroids In Premenopausal Women. See Important Safety And Potential Side Effects Information On The Patient Site.

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  1. Apr 24, 2021 · COVID-19 vaccines, irregular periods and spike protein shedding. April 24, 2021. Are irregular periods a side effect of COVID-19 vaccines? Irregular periods include heavier bleeding than normal, early periods, late periods and similar changes. Right now, there’s no scientific evidence that suggests COVID-19 vaccines are making periods irregular.

  2. Jul 19, 2022 · Both COVID-19-related spike protein and adjuvants used in vaccination have been considered possible culprits. COVID-19-related spike protein is found on the surface of the SARS-COV-2 virus.

    • 10.1016/j.vacun.2022.07.001
    • September-December 2022
    • Overview
    • Widespread effect

    Women who don’t menstruate — including postmenopausal women and those on contraceptives — were several times more likely to experience unexpected vaginal bleeding after COVID-19 vaccination than before the vaccines were offered, a study1 finds.

    When COVID-19 jabs were rolled out globally, many women reported heavier-than-usual menstrual bleeding soon after vaccination. Study author Kristine Blix, at the Norwegian Institute of Public Health in Oslo, wanted to look at the trend systematically, particularly in women who don’t normally have periods, such as those taking contraceptives or who have been through menopause. The work is published in Science Advances.

    The team didn’t investigate the reasons for the unexplained bleeding, but suggested that it could be linked to the SARS-CoV-2 spike protein used in the vaccines. In general, the COVID-19 vaccines have been found to be safe and effective.

    Blix and her colleagues used an ongoing population health survey called the Norwegian Mother, Father, and Child Cohort Study. “We had already, from the early pandemic, biweekly questionnaires going out to cohort participants to monitor effects of the pandemic,” Blix says. In the first questionnaire that covered COVID-19 vaccinations, sent in 2021, some women reported in free-text fields that they had experienced heavy menstrual bleeding. “This urged us to ask for bleeding patterns in a structured manner,” she says.

    The team looked at more than 21,000 responses from postmenopausal, perimenopausal and non-menstruating premenopausal women — including some who were on long-term hormonal contraceptives.

    The results were surprising, says Blix. They found that 252 postmenopausal women, 1,008 perimenopausal women and 924 premenopausal women reported experiencing unexpected vaginal bleeding.

    Of these, roughly half of each group said that the bleeding came in the four weeks after the first or second vaccine dose, or both. Premenopausal and perimenopausal women were most likely to report unexpected bleeding in the month after the vaccine, with their risk being three to five times as high as before the vaccinations existed. The risk for postmenopausal women increased by two- to threefold.

    Norway used the mRNA jabs made by Moderna and Pfizer–BioNTech, and other vaccines including the one made by AstraZeneca. In October 2022, the European Medicines Agency updated the side-effect information of mRNA vaccines to include heavy menstrual bleeding.

    Unexpected bleeding after menopause is usually considered medically serious, and could be an early sign of conditions including endometrial carcinoma and precancerous lesions. Although the cause of the post-vaccination bleeding isn’t clear, if it’s a known side-effect of the shots, physicians can take this into account when evaluating a patient’s condition. “Postmenopausal bleeding is often very concerning and a possible sign of cancer. Knowing a patient’s vaccination status could put their bleeding incidence into context, ” says Kate Clancy, a biological anthropologist at the University of Illinois Urbana-Champaign.

    Clancy’s group has published results2 of their own survey showing changes in menstrual bleeding after COVID-19 vaccination. She says that the results align with her team’s findings and could help to inform patients and clinicians.

  3. Mar 9, 2022 · Based on these elements, we decided to investigate the occurrence of menstrual irregularities and abnormal uterine bleeding after the first and second doses of the COVID-19 vaccine, correlate these cases to the type of vaccine administered, and evaluate how long this effect lasted.

  4. May 12, 2021 · The spike protein, which cannot reproduce, then disintegrates or is destroyed. The mRNA - the instruction to make the spike protein - is also extremely fragile.

    • spike protein shedding and menstrual bleeding1
    • spike protein shedding and menstrual bleeding2
    • spike protein shedding and menstrual bleeding3
    • spike protein shedding and menstrual bleeding4
  5. Sep 22, 2023 · The European Medicines Agency recently decided that the product information of the mRNA vaccines (i.e., Spikevax and Comirnaty) should be updated to include heavy menstrual bleeding as a potential side effect ( 5 ).

  6. May 11, 2021 · Yet several online posts falsely claim that vaccinated people are “shedding” the SARS-CoV-2 spike protein, which is what the virus uses to enters cells, through their “ breath ” and “...

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