Search results
Aug 1, 2023 · Monoclonal gammopathy of undetermined significance (MGUS) is a condition in which an atypical protein is found in the blood. The protein is called monoclonal protein or M protein. This protein is made in the soft, blood-producing tissue in the center of bones.
Aug 1, 2023 · Urine samples taken over 24 hours can help find if the atypical protein is in the urine. They also can check for kidney damage. Imaging tests. For people with bone pain, an, MRI or positron emission tomography (PET) scan can look for problems with bones from MGUS.
Jul 25, 2022 · What is monoclonal gammopathy of undetermined significance (MGUS)? Monoclonal gammopathy of undetermined significance (MGUS) is a blood disorder that affects plasma cells in your bone marrow. Most of the time, M proteins don’t cause issues and most people with MGUS don’t have symptoms.
Monoclonal gammopathy of undetermined significance (MGUS) is not cancer. There’s a small risk it can become cancer. Out of every 100 people with MGUS, each year, 1 or 2 of them will get cancer from MGUS.
May 31, 2024 · Monoclonal gammopathy of undetermined significance (MGUS) is a clinically asymptomatic premalignant clonal plasma cell or lymphoplasmacytic proliferative disorder. It is defined by the presence of a serum monoclonal protein (M protein) at a concentration <3 g/dL, a bone marrow with <10 percent monoclonal plasma cells, and absence of end-organ ...
Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic (showing no symptoms) condition in which an abnormal monoclonal protein (M protein) is present in the blood. Monoclonal means there is only one type of this abnormal protein derived from a single cell.
Jul 10, 2022 · Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic premalignant plasma cell disorder that is characterized by the presence of serum M-protein less than 30 g/L or 3 g/dL, bone marrow (BM) clonal plasma cells less than 10%, absence of plasma cell myeloma (PCM) related end-organ damage (CRAB symptoms: hypercalcemia, renal ...
Jun 6, 2019 · Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma cell dyscrasia that consistently precedes multiple myeloma (MM) with a 1% risk of progression per year.
Monoclonal gammopathy of undetermined significance (MGUS) is the production of M-protein by noncancerous plasma cells in the absence of other manifestations typical of multiple myeloma. (See also Overview of Plasma Cell Disorders.)
In general, monoclonal gammopathy of undetermined significance (MGUS) occurs in more than 5% of people older than 70, but it does not cause significant health problems unless it progresses to myeloma or a related serious B-cell disorder.
