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  1. Nov 28, 2022 · It’s also possible that actinic keratosis can go away on its own. This is called regression and is estimated to happen in 25% to 50% of people. Actinic keratosis can also recur after treatment ...

    • Sian Ferguson
    • 5-fluorouracil. “One of the widely used and most effective prescription at-home therapies is topical chemotherapy called 5-fluorouracil,” Pratt says.
    • Diclofenac sodium. Diclofenac sodium gel (Solaraze, Cambia, Voltaren) is a topical nonsteroidal anti-inflammatory drug (NSAID) that can help treat actinic keratosis.
    • Imiquimod. You may get a prescription for this medication if you have actinic keratoses on your face and scalp. This medication works by affecting your body’s immune response to skin lesions.
    • Ingenol mebutate. You’ll apply this medication gel once a day for 2 or 3 days in a row and leave it on for about 6 hours before washing it off. Your dermatologist will give you more specific, personalized directions on using this treatment.
  2. Actinic keratosis is a pre-cancerous skin lesion on the skin. They are usually rough, scaly patches that form on the areas that receive extensive sun exposure: the face, lips, ears, backs of the hands, forearms, scalp, or neck. These growths develop slowly and don’t have any signs or symptoms other than their appearance.

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  4. Patients first notice actinic keratosis as a scaly, gritty sensation on the face. Sometimes, it takes on a red color. It feels thick and flaky, almost like a scab that never quite heals. In some cases, it fades and reappears over a long period of time. These spots come and go as the body fights unhealthy cells.

  5. While most people see only a change to their skin, an AK can: Itch. Burn or sting. Feel tender or painful when touched. Stick to your clothing, causing discomfort. Bleed. If you find a change on your skin that could be an actinic keratosis, protect your health by seeing a board-certified dermatologist.

  6. Treatment. |. Actinic keratoses (solar keratoses) are precancerous growths caused by long-term sun exposure. Many years of sun exposure can cause actinic keratoses to develop on the skin. Actinic keratoses are rough and scaly and appear in various colors. The diagnosis is usually based on a doctor's evaluation.