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Nobel Prize in Science. César Milstein was awarded the 1984 Nobel Prize in Physiology or Medicine jointly with his former postdoctoral fellow Georges J. F. Köhler (AAI '85) and theoretician Niels Jerne (AAI '73). Milstein and Köhler won the prize for developing the hybridoma method of producing monoclonal antibodies.
Jun 1, 2002 · 3 Altmetric. Metrics. In memoriam: César Milstein, who with the late Georges Köhler invented monoclonal antibodies, died on 24 March 2002. Their invention sprang from basic research on antibody...
- Timothy A. Springer
- 2002
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Having been a strongly anti-Peronist president of the student union, Milstein risked attracting the unwelcome attention of the military government. To support himself during his studies, he worked part time at the Laboratorios Liebeschutz, a clinical biochemistry laboratory.
Milstein's father, Lazaro, was born in a village in the Ukraine and migrated to Argentina in 1913 at the age of 14 with his aged aunt and uncle. For many years he lived in Jewish settlements near Bahía Blanca trying his hand at different trades, including farm labour, carpentry and railway work. During this time he taught himself Spanish and ...
Apr 30, 2002 · César Milstein, who died on 24 March, spent the major part of his research career working on antibodies, making outstanding contributions to both areas. Behring's discovery was recognised by the award in 1901 of the first Nobel Prize in Physiology or Medicine.
- Michael Neuberger
- 2002
Jun 1, 2002 · It will not be an exaggeration to describe César Milstein's contribution to science and medicine as one of the most important ever made, and the engineering of monoclonal antibodies was by far the most important immunological discovery of the past century. The ability to produce monoclonal antibodies in the test tube, in unlimited quantities and to any sort of antigen, opened unforeseen ...
Apr 25, 2002 · César Milstein began to study antibody diversity at a time when almost nothing was known about its molecular and genetic basis. As a logical step in that work, with Georges Köhler he devised the ...