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César Milstein, CH, FRS (8 October 1927 – 24 March 2002) was an Argentine biochemist in the field of antibody research. Milstein shared the Nobel Prize in Physiology or Medicine in 1984 with Niels Kaj Jerne and Georges J. F. Köhler for developing the hybridoma technique for the production of monoclonal antibodies.
Jun 1, 2002 · Wilson Savino. Nature Immunology (2008) In memoriam: César Milstein, who with the late Georges Köhler invented monoclonal antibodies, died on 24 March 2002. Their invention sprang from basic ...
- Timothy A. Springer
- 2002
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César Milstein, Ph.D. Brief Bio. César Milstein was born in Bahia Blanca, Argentina, on October 8, 1927. His father, a Jewish immigrant who made the journey from Ukraine to Argentina by himself as a teenager, and his mother, a teacher who was raised in a working class, immigrant family, made education a priority for César and his two brothers and encouraged them to attend university.
Wade went on to argue: 'The Wistar Institute seems in a sense to have jumped into the gap which Milstein and Köhler left. A broad patent for monoclonal antibodies raised against tumour cells was granted on 23 October 1979 to Hilary Koprowski and Carlo Croce. A similar broad patent covering the antibodies to viral antigens was issued on 1 April ...
Dec 2, 2016 · On 7 August 1975, Nature published a three-page report by César Milstein and Georges J. F. Köhler describing a method for generating large amounts of monoclonal antibodies of a predefined ...
Milstein, César, (8 Oct. 1927–24 March 2002), Scientific Staff of Medical Research Council, 1963–95; Fellow, Darwin College, University of Cambridge, 1981–95, Hon. Fellow, 2002; Joint Head, Division of Protein and Nucleic Acid Chemistry, 1981–93, Deputy Director, 1988–95, MRC Laboratory of Molecular Biology in Who Was Who
Apr 25, 2002 · Klaus Rajewsky. Nature 416 , 806 ( 2002) Cite this article. 1200 Accesses. 3 Altmetric. Metrics. Innovator in immunology Credit: MRC LMB. César Milstein began to study antibody diversity at a...
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