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Nov 11, 2018 · A computational method was proposed to prioritize functional CRs in cancer; this method integrates genetic mutations, gene expression, miRNA regulation, protein–protein interaction networks (PPIN), and regulation of epigenetic modifications.
- Jianping Lu, Juan Xu, Junyi Li, Tao Pan, Jing Bai, Liqiang Wang, Xiyun Jin, Xiaoyu Lin, Yunpeng Zhan...
- 10.1093/nar/gky679
- 2018
- 2018/11/11
An alpha helix (or α-helix) is a sequence of amino acids in a protein that are twisted into a coil (a helix). The alpha helix is the most common structural arrangement in the secondary structure of proteins .
In this chapter, you will learn about the components of protein, the important roles that protein serves within the body, how the body uses protein, the risks and consequences associated with too much or too little protein, and where to find healthy sources of it in your diet.
Oct 31, 2023 · A protein’s shape determines its function. Proteins are composed of amino acid subunits that form polypeptide chains. Enzymes catalyze biochemical reactions by speeding up chemical reactions, and can either break down their substrate or build larger molecules from their substrate.
Jan 17, 2024 · Proper protein intake enables the basic biological processes of the body to maintain the status quo in a changing environment. Fluid balance refers to maintaining the distribution of water in the body. If too much water in the blood suddenly moves into a tissue, the results are swelling and, potentially, cell death.
Aug 10, 2022 · A protein may have up to four levels of structure. The primary structure consists of the specific amino acid sequence. The resulting peptide chain can form an α-helix or β-pleated sheet (or local structures not as easily categorized), which is known as secondary structure.
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Sep 15, 2023 · The decoding of genetic information to synthesize a protein is the central foundation of modern biology. The building of a protein consists of a complex series of chemical reactions that can be summarized into three basic steps: transcription, translation, and protein folding. Figure \(\PageIndex{3}\): Overview of protein synthesis.
