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  2. Nov 15, 2022 · 11/15/2022. Published in Discovery - Winter 2023. “Don’t worry about Gleason 3+3=6 (Grade Group 1)! It’s harmless! In fact, we shouldn’t even call it cancer!”. Many patients have heard reassurances like these, and yes, if you have to have prostate cancer, Grade Group 1 is the best kind to have.

  3. For example, if the Gleason score is written as 3+4=7, it means most of the tumor is grade 3 and less is grade 4, and they are added for a Gleason score of 7. Other ways that this Gleason score might be listed in your report are Gleason 7/10, Gleason 7 (3+4), or combined Gleason grade of 7.

    • Overview
    • Gleason Score
    • Categories
    • Grade Groups
    • Importance

    This article explains the Gleason score, which is used to determine how quickly prostate cancer might grow and what kind of treatment plan healthcare providers should develop for patients with prostate cancer.

    The Gleason score is a factor healthcare providers consider to develop your treatment plan for prostate cancer. It reflects what they learned about your cancer after examining tissue samples from your biopsy and grading each piece of the pattern on a 3 to 5 scale.

    Providers break down the scores into three categories, well differentiated (Gleason 6 or lower), moderately differentiated (Gleason 7) and poorly differentiated or undifferentiated (Gleason 8, 9 or 10).

    Healthcare providers established grade groups to clarify the system with five groups ranging from 1-5 based on their scores.

    The scores predict how quickly prostate cancer might grow but are not good or bad per se and aren't the only factors considered when creating a treatment plan.

  4. The main stages of prostate cancer range from I (1) through IV (4). Some stages are split further (IIA, IIB, IIC, etc.). As a rule, the lower the number, the less the cancer has spread. A higher number, such as stage IV, means cancer has spread more. And within a stage, an earlier letter means a lower stage.

  5. Sep 8, 2023 · Grade 1. The cells look very much like normal prostate cells. Grades 2-4. Cells that score lower look closest to normal and represent a less aggressive cancer. Those that score higher look the...

  6. The pathologist looking at the biopsy sample will assign one Gleason grade to the most predominant pattern in your biopsy and a second Gleason grade to the second most predominant pattern. For example: 3 + 4.

  7. Feb 22, 2024 · If the primary pattern, or the most common pattern, is grade 3 and the secondary pattern is grade 4, the Gleason score is 3+4=7. If the tumor is the same grade everywhere, that grade is added...

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