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  1. The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β 2) agonists and alpha-2 (α 2) agonists, which are used to treat high blood ...

  2. May 5, 2020 · A high-resolution description of β 1 -adrenergic receptor functional dynamics and allosteric coupling from backbone NMR. Anne Grahl, Layara Akemi Abiko, Shin Isogai, Timothy Sharpe & Stephan...

    • Anne Grahl, Layara Akemi Abiko, Shin Isogai, Timothy Sharpe, Stephan Grzesiek
    • 2020
  3. Jun 24, 2021 · Adrenergic receptors are G protein-coupled receptors for epinephrine and norepinephrine. They are targets of many drugs for various conditions, including treatment of hypertension, hypotension, and asthma. Adrenergic receptors are intensively studied in structural biology, displayed for binding poses of different types of ligands.

    • Yiran Wu, Liting Zeng, Suwen Zhao
    • 10.3390/biom11070936
    • 2021
    • Biomolecules. 2021 Jul; 11(7): 936.
  4. Sep 20, 2023 · Nature - Stress-associated catecholamines promote CD8+ T cell exhaustion through the β1-adrenergic receptor, and blocking β-adrenergic signalling may help restore anti-tumour...

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  6. Aug 14, 2023 · Beta-1 receptors, along with beta-2, alpha-1, and alpha-2 receptors, are adrenergic receptors primarily responsible for signaling in the sympathetic nervous system. Beta-agonists bind to the beta receptors on various tissues throughout the body.

  7. Nov 1, 2011 · Figure 1. An overview on regulation of βAR function. Go to: βAR Signaling. β1 and β2ARs are the most well-studied members of the βAR family comprising of three members; β1, β2 and β3ARs. βARs are one of the most powerful regulators of cardiac function among the estimated 200 GPCRs in the heart.

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