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  1. Conclusions: Mepolizumab may be effective in elderly patients with eosinophilic asthma and ACO. Keywords: Asthma and chronic obstructive pulmonary disease overlap; Elderly patient; Eosinophil; Interleukin-5; Severe asthma.

  2. www.nomuraholdings.com › company › groupLeadership Team | NOMURA

    Jun 5, 2024 · Leadership Team. Senior Managing Directors include Executive Managing Directors and Senior Managing Directors of Nomura Holdings, Nomura Securities SMDs, as well as group SMDs appointed by the Nomura Holdings Executive Management Board. As of June 5, 2024.

    Name
    Position
    Kentaro Okuda
    President and Group CEO of Nomura ...
    Tomoyuki Teraguchi
    Vice Chairman of Nomura Holdings, Inc.
    Yutaka Nakajima
    Representative Executive Officer, Deputy ...
    Toshiyasu Iiyama
    Executive Officer, Deputy President of ...
  3. Jun 6, 2022 · We enrolled 12 elderly patients (age ≥65 years) with severe eosinophilic asthma treated with mepolizumab at Hiroshima Prefectural Hospital (Hiroshima, Japan) during the study period. Six patients were switched from mepolizumab to benralizumab, and six continued with the mepolizumab treatment.

    • 10.2169/internalmedicine.8180-21
    • 2022/06/06
    • Intern Med. 2022 Jun 1; 61(11): 1663-1671.
  4. Apr 26, 2024 · Akio Nomura, a long-time board game designer and board member of Japon Brand, becomes president of the company following the buyout. He said, “The situation surrounding the analogue game industry in Japan has been changing over the past ten years.

  5. Dec 13, 2019 · Diquafosol is a P2Y 2 receptor agonist that is approved for the treatment of dry eye disease (DED) in Japan. Short-term treatment with diquafosol was effective and safe in a prospective, observational, post-marketing study.

    • Yuichi Ohashi, Masahiro Munesue, Jun Shimazaki, Etsuko Takamura, Norihiko Yokoi, Hitoshi Watanabe, A...
    • 10.1007/s12325-019-01188-x
    • 2020
    • Adv Ther. 2020; 37(2): 707-717.
  6. Jun 2, 2022 · Abstract. Objective Switching from mepolizumab to benralizumab has been reported to significantly improve both asthma control and the lung function. However, the data on its efficacy in elderly patients with severe eosinophilic asthma are limited.

  7. Jul 1, 2021 · Thirty-three elderly patients (aged ≥65 years), diagnosed with severe eosinophilic asthma and treated at Hiroshima Prefectural Hospital (Hiroshima, Japan) between August 2016 and March 2019, were identified.

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