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- The median plasma CRP concentration was 1.53 mg/L (IQR, 1.14-2.51) and 34% of the participants had circulating CRP levels of ≥2 mg/L. Epidemiologic studies suggest that in patients with several types of solid cancers, elevated circulating levels of CRP are associated with poor prognosis, whereas in apparently healthy individuals from the general population, elevated levels of CRP are associated with increased future risk of cancer of any type, lung cancer, and possibly colorectal cancer, but not...
pubmed.ncbi.nlm.nih.gov › 22035340Elevated C-reactive protein in the diagnosis, prognosis, and ...
Nov 19, 2020 · This report focuses on innate immunity and the acute phase response (APR) to cancerous growth. More specifically, it provides a new perspective on the diagnostic and therapeutic value of the prototypic acute phase reactant, C-reactive protein (CRP), and cancer.
- Table - PMC - National Center for Biotechnology Information
• Higher CRP levels are a poor prognostic indicator in large...
- Figure - PMC - National Center for Biotechnology Information
Graphic representation of data summarized in Table 1.The CRP...
- C-Reactive Protein Is an Important Biomarker for Prognosis ...
High sensitivity CRP (hs-CRP), tumoral CRP and CRP kinetics...
- Elevated C-reactive protein in the diagnosis, prognosis, and ...
The robust association between circulating levels of CRP and...
- Serum C-reactive protein is an important and powerful ...
Prognostication in cancer is challenging and inaccurate....
- C-Reactive Protein and Cancer-Diagnostic and Therapeutic ...
C-reactive protein (CRP) is a predominant protein of the...
- Table - PMC - National Center for Biotechnology Information
People also ask
Is CRP prognostic?
Does a high CRP predict a prognosis of solid tumors?
Does high CRP predict survival in colorectal cancer?
High sensitivity CRP (hs-CRP), tumoral CRP and CRP kinetics have also been utilized for disease progression and prognosis. Increased hs-CRP has been associated with late recurrence in renal cell carcinoma [ 119 ] and with increased mortality in breast cancer [ 79 ] and in men with lung cancer [ 118 ].
- Shiva Shrotriya, Declan Walsh, Nabila Bennani-Baiti, Shirley Thomas, Cliona Lorton
- 10.1371/journal.pone.0143080
- 2015
- PLoS One. 2015; 10(12): e0143080.
Apr 24, 2019 · Sensitivities for cancer were 46.1% for CRP, 43.6% ESR and 49.7% for PV. Cancer should be considered in patients with raised inflammatory markers.
- Jessica Watson, Chris Salisbury, Jonathan Banks, Penny Whiting, Willie Hamilton
- 2019
The robust association between circulating levels of CRP and cancer risk may be due to (1) causality: elevated CRP levels cause cancer, (2) reverse causality: occult cancer increases CRP levels, (3) or confounding: a third factor, e.g. inflammation, increases both CRP levels and the risk of cancer.
- Kristine H. Allin, Børge G. Nordestgaard
- 2011
Aug 23, 2018 · Prognostication in cancer is challenging and inaccurate. C-Reactive Protein (CRP), a cheap and sensitive marker of inflammation may help. This study investigated the relationship between CRP and prognosis in a large cohort of solid tumors with mixed cancer diagnoses and stages.
- Shiva Shrotriya, Declan Walsh, Amy S. Nowacki, Cliona Lorton, Aynur Aktas, Barbara Hullihen, Nabila ...
- 10.1371/journal.pone.0202555
- 2018
- PLoS One. 2018; 13(8): e0202555.
Dec 22, 2022 · Results for an hs-CRP test are usually given as follows: Lower risk of heart disease: Less than 2.0 mg/L; Higher risk of heart disease: Equal to or greater than 2.0 mg/L; A person's CRP levels vary over time. A coronary artery disease risk assessment should be based on the average of two hs-CRP tests. It's best if they're taken two weeks apart.
Nov 19, 2020 · C-reactive protein (CRP) is a predominant protein of the acute phase response; its blood levels have long been used as a minimally invasive index of any ongoing inflammatory response, including that occurring in cancer. Its diagnostic significance in assessing disease progression or remission, however, remains undefined.
