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- Spherocytosis can make a person susceptible to severe anemia or infections. A severely enlarged spleen could rupture, which is dangerous.
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Hereditary spherocytosis is an inherited blood disorder that causes hemolytic anemia. This anemia happens when your red blood cells break down faster than normal.
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Feb 16, 2022 · Spherocytosis is a condition that causes a person’s red blood cells to be shaped like spheres (round balls) instead of their normal disk shape. It can cause symptoms of anemia (lack of healthy red blood cells) and an enlarged spleen (an organ that filters and stores blood).
Aug 5, 2019 · Severe anemia can cause serious, even life-threatening, complications if left untreated. Individuals with severe forms of HbH disease are usually treated with regular blood transfusions, which can result in the accumulation of excess iron in the body (iron overload).
Jul 4, 2023 · Approximately 50% of patients with hereditary spherocytosis present with anemia, and 10 to 15% with splenomegaly or jaundice. The majority of patients will present partially compensating hemolysis in addition to mild anemia.
- Edgar A. Zamora, Catherine A. Schaefer
- 2023/07/04
Mar 15, 2023 · Anemia (lack of blood) symptoms can vary depending on the cause. Symptoms may include fatigue, pale skin, heart palpitations, shortness of breath, and dizziness. There are several anemia types.
Mar 6, 2023 · This can cause anemia, which means that a person does not have enough red blood cells. Anemia affects the body’s ability to carry oxygen, potentially affecting many areas of functioning.
Oct 25, 2023 · Although relatively rare, hereditary spherocytosis (HS) is the most common cause of hemolytic anemia due to a red cell membrane defect. It is a result of heterogeneous alterations in one of five genes that encode red blood cell (RBC) membrane proteins involved in vertical associations that link the membrane cytoskeleton to the lipid bilayer.
